[HTML][HTML] Vascular dysfunction in preeclampsia
MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
[HTML][HTML] Pathophysiological implications of hypoxia in human diseases
Oxygen is essentially required by most eukaryotic organisms as a scavenger to remove
harmful electron and hydrogen ions or as a critical substrate to ensure the proper execution …
harmful electron and hydrogen ions or as a critical substrate to ensure the proper execution …
[HTML][HTML] The impact of hypoxia in early pregnancy on placental cells
H Zhao, RJ Wong, DK Stevenson - International journal of molecular …, 2021 - mdpi.com
Oxygen levels in the placental microenvironment throughout gestation are not constant, with
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
[HTML][HTML] Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta
BV Natale, KN Gustin, K Lee, AC Holloway… - Scientific reports, 2020 - nature.com
Abstract 1 in 5 women report cannabis use during pregnancy, with nausea cited as their
primary motivation. Studies show that (-)-△ 9–tetrahydrocannabinol (Δ9-THC), the major …
primary motivation. Studies show that (-)-△ 9–tetrahydrocannabinol (Δ9-THC), the major …
Animal models of preeclampsia: causes, consequences, and interventions
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …
[HTML][HTML] Distinct placental molecular processes associated with early-onset and late-onset preeclampsia
Z Ren, Y Gao, Y Gao, G Liang, Q Chen, S Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Patients with preeclampsia display a spectrum of onset time and severity of
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …
[HTML][HTML] Human chorionic villous differentiation and placental development
J Kojima, M Ono, N Kuji, H Nishi - International Journal of Molecular …, 2022 - mdpi.com
In humans, the placenta provides the only fetomaternal connection and is essential for
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …
[HTML][HTML] Hypoxia and mitochondrial dysfunction in pregnancy complications
Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …
hypoxia during gestation is associated with significantly increased incidence of maternal …
[HTML][HTML] Iron metabolism and ferroptosis: A pathway for understanding preeclampsia
KE Gumilar, B Priangga, CH Lu, EG Dachlan… - Biomedicine & …, 2023 - Elsevier
Preeclampsia (PE) is a serious medical condition that poses a significant health risk to
women and children worldwide, particularly in the middle-and low-income countries. It is a …
women and children worldwide, particularly in the middle-and low-income countries. It is a …
Maternal microbiome in preeclampsia pathophysiology and implications on offspring health
JA Ishimwe - Physiological reports, 2021 - Wiley Online Library
Preeclampsia is a devastating hypertensive pregnancy disorder that currently affects 2%–
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …