[HTML][HTML] Participation of Single-Nucleotide Variants in IFNAR1 and IFNAR2 in the Immune Response against SARS-CoV-2 Infection: A Systematic Review

MF López-Bielma, R Falfán-Valencia, E Abarca-Rojano… - Pathogens, 2023 - mdpi.com
Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …

Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort

M Skerenova, M Cibulka, Z Dankova… - Advances in Medical …, 2024 - Elsevier
We present the results of an association study involving hospitalized coronavirus disease
2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of …

[HTML][HTML] Genetic loci associated with COVID-19 positivity and hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program

GM Peloso, C Tcheandjieu, JE McGeary… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 has caused symptomatic COVID-19 and widespread death across the globe.
We sought to determine genetic variants contributing to COVID-19 susceptibility and …

[HTML][HTML] A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility

G Voloudakis, JM Vicari, S Venkatesh… - NPJ Genomic …, 2022 - nature.com
Recent efforts have identified genetic loci that are associated with coronavirus disease 2019
(COVID-19) infection rates and disease outcome severity. Translating these genetic findings …

[HTML][HTML] Association between lipid levels and risk for different types of aneurysms: a Mendelian randomization study

Y Chen, M Huang, Y Xuan, K Li, X Xu, L Wang… - Journal of Personalized …, 2021 - mdpi.com
Background: Although the associations between serum lipid levels and aneurysms have
been investigated in epidemiological studies, causality remains unknown. Thus, this study …

Interleukin-18 and COVID-19

CM Schooling, M Li, SLA Yeung - Epidemiology & Infection, 2022 - cambridge.org
Vulnerability to coronavirus disease (COVID)-19 varies due to differences in interferon
gamma (IFNγ) immunity. We investigated whether a key modifiable interferon precursor …

Molecular PET/CT mapping of rhACE2 distribution and quantification in organs to aid in SARS‐CoV‐2 targeted therapy

Z Wang, C Zhao, C Li, S Liu, J Ding… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, poses a significant threat to …

An integrated strategy to identify COVID‐19 causal genes and characteristics represented by LRRC37A2

Z Zhu, X Chen, C Wang, S Zhang, R Yu… - Journal of Medical …, 2023 - Wiley Online Library
Genome‐wide association study (GWAS) could identify host genetic factors associated with
coronavirus disease 2019 (COVID‐19). The genes or functional DNA elements through …

[HTML][HTML] An evolutionary insight into the heterogeneous severity pattern of the SARS-CoV-2 infection

RZ Raza, SW Abbasi - Frontiers in Genetics, 2022 - frontiersin.org
The ongoing pandemic of COVID-19 has elaborated an idiosyncratic pattern of SARS-CoV-2-
induced symptoms in the human host. Some populations have succumbed to the SARS-CoV …

[HTML][HTML] Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease

Y Qiu, Y Hou, D Gohel, Y Zhou, J Xu, M Bykova… - Cell Reports, 2024 - cell.com
Shifts in the magnitude and nature of gut microbial metabolites have been implicated in
Alzheimer's disease (AD), but the host receptors that sense and respond to these …