The ingression of a cleavage furrow separates the two daughter cells at the end of cell
division. In many organisms this furrow ingression is driven by the assembly and contraction …

Spatial and timely coordination of cytokinesis is crucial for the maintenance of organelle
inheritance and genome integrity. The mitotic exit network (MEN) pathway controls both the …

We developed a method to highly purify germline stem cells (GSCs) from the Drosophila
ovary, one of the best understood types of adult stem cell. GSCs express variant isoforms of …

Abstract The F-BAR protein Cdc15 is essential for cytokinesis in Schizosaccharomyces
pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane …

Two prevailing models have emerged to explain the mechanism of contractile-ring assembly
during cytokinesis in the fission yeast Schizosaccharomyces pombe: the spot/leading cable …

Diaphanous-related formin, mDia, is an actin nucleation/polymerization factor functioning
downstream of the small GTPase Rho. Although Rho is critically involved in cytokinesis, it …

In many eukaryotes, cytokinesis requires the assembly and constriction of an actomyosin-
based contractile ring. Despite the central role of this ring in cytokinesis, the mechanism of F …

The flexibility displayed by apicomplexan parasites to vary their mode of replication has
intrigued biologists since their discovery by electron microscopy in the 1960s and 1970s …

The mitotic-exit network (MEN) is a signaling pathway that is essential for the coordination of
mitotic exit and cytokinesis. Whereas the role of the MEN in mitotic exit is well established …

Cytokinesis is essential for cell proliferation in all domains of life. Because the core
components and mechanisms of cytokinesis are conserved from fungi to humans, the …