Cytokinesis is essential for the survival of all organisms. It requires concerted functions of
cell signaling, force production, exocytosis, and extracellular matrix remodeling. Due to the …

The role of the actin-depolymerizing factor (ADF)/cofilin-family protein Adf1 in cytokinesis of
fission yeast cells was studied. Adf1 was required for accumulation of actin at the division …

The functions of the actin-myosin–based contractile ring in cytokinesis remain to be
elucidated. Recent findings show that in the fission yeast Schizosaccharomyces pombe …

Immunoconjugates composed of the α-emitter 213 Bi and the monoclonal antibody d9MAb
specifically target HSC45-M2 gastric cancer cells expressing mutant d9-E-cadherin. These …

Budding yeast (Saccharomyces cerevisiae) and fission yeast (Schizosaccharomyces
pombe) are two popular model organisms for virus research. They are natural hosts for …

Summary The small GTPase Rho and mDia2, a Rho-regulated actin nucleator, function as
critical regulators of cytokinesis in cultured cells. However, their involvement in cytokinesis …

Cytokinesis, which leads to the physical separation of two dividing cells, is normally
restrained until after nuclear division. In Saccharomyces cerevisiae, chitin synthase 2 …

A small GTPase, Arf6, is involved in cytokinesis by localizing to the Flemming body (the
midbody). However, it remains unknown how Arf6 contributes to cytokinesis. Here, we …

In this review article, yeast model-based research advances regarding the role of Amyloid-β
(Aβ), Tau and frameshift Ubiquitin UBB+ 1 in Alzheimer's disease (AD) are discussed …

The cell division cycle is tightly regulated by the activation and inactivation of a series of
proteins that control the replication and segregation of organelles to the daughter cells …