Formins are conserved actin nucleators which promote the assembly of actin filaments for
the formation of diverse actin structures. In fission yeast Schizosaccharomyces pombe, the …

By rapidly depleting each of the essential budding yeast proteins of unknown function, we
identified a novel factor that we call Inn1, which associates with the contractile actomyosin …

Abstract Megakaryoblastic leukemia 1 (MKL1), identified as part of the t (1; 22) translocation
specific to acute megakaryoblastic leukemia, is highly expressed in differentiated muscle …

International Review of Cell and Molecular Biology presents current advances and
comprehensive reviews in cell biology--both plant and animal. Articles address structure and …

In somatic cell division, cytokinesis is the final step of the cell cycle and physically divides
the mother cytoplasm into two daughter cells. In the meiotic cell division, however, pollen …

The budding yeast Saccharomyces cerevisiae has an actin cytoskeleton that comprises a
set of protein components analogous to those found in the actin cytoskeletons of higher …

Cell division in many eukaryotes is driven by a ring containing actin and myosin. While much
is known about the main proteins involved, the precise arrangement of actin filaments within …

Both de novo–assembled actin filaments at the division site and existing filaments recruited
by directional cortical transport contribute to contractile ring formation during cytokinesis …

Microtubules of the mitotic spindle are believed to provide positional cues for the assembly
of the actin-based contractile ring and the formation of the subsequent cleavage furrow …

The question of how the site for division of the cytoplasm is determined at the end of mitosis
has been studied for over a century, and it remains an active, controversial and fascinating …