[HTML][HTML] Cytomegalovirus infection in transplant recipients

LS Azevedo, LC Pierrotti, E Abdala, SF Costa… - Clinics, 2015 - SciELO Brasil
Cytomegalovirus infection is a frequent complication after transplantation. This infection
occurs due to transmission from the transplanted organ, due to reactivation of latent …

Infection in solid-organ transplant recipients

JA Fishman - New England Journal of Medicine, 2007 - Mass Medical Soc
Increasingly potent immunosuppressive agents have dramatically reduced the incidence of
rejection of transplanted organs while increasing susceptibility to opportunistic infections …

Cytomegalovirus latency and reactivation: recent insights into an age old problem

L Dupont, MB Reeves - Reviews in medical virology, 2016 - Wiley Online Library
Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient
populations. In certain clinical settings, it is the reactivation of the pre‐existing latent infection …

Human cytomegalovirus and kidney transplantation: a clinician's update

K De Keyzer, S Van Laecke, P Peeters… - American journal of …, 2011 - Elsevier
Infection with human cytomegalovirus (CMV) is an important cause of morbidity and mortality
in kidney transplant recipients. CMV disease is diagnosed based on the detection of viral …

Protection from cytomegalovirus viremia following glycoprotein B vaccination is not dependent on neutralizing antibodies

I Baraniak, B Kropff, L Ambrose… - Proceedings of the …, 2018 - National Acad Sciences
Human cytomegalovirus (HCMV) is an important pathogen in transplant patients and in
congenital infection. Previously, we demonstrated that vaccination with a recombinant viral …

[HTML][HTML] Cytomegalovirus therapy: role of letermovir in prophylaxis and treatment in transplant recipients

JL Saullo, RA Miller - Annual Review of Medicine, 2023 - annualreviews.org
Cytomegalovirus (CMV) is a common viral pathogen in the transplant population and is
associated with significant morbidity and mortality. CMV prevention is paramount; however …

Seropositivity and higher immunoglobulin G antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective …

E Gkrania-Klotsas, C Langenberg… - Clinical infectious …, 2013 - academic.oup.com
Background. The relationship between cytomegalovirus (CMV) infection and mortality
among immunocompetent individuals is uncertain. We aimed to examine whether …

Inhibition of inflammatory interleukin-6 activity via extracellular signal-regulated kinase–mitogen-activated protein kinase signaling antagonizes human …

MB Reeves, T Compton - Journal of virology, 2011 - Am Soc Microbiol
Human cytomegalovirus (HCMV) remains a major cause of viral disease in
immunosuppressed transplant patients. The ability of HCMV to establish lifelong infection in …

Evaluation of cytomegalovirus (CMV)-specific T cell immune reconstitution revealed that baseline antiviral immunity, prophylaxis, or preemptive therapy but not …

D Abate, A Saldan, M Fiscon, S Cofano… - The Journal of …, 2010 - academic.oup.com
Background. The ultimate goal of organ transplantation is the reestablishment of organ
function and the restoration of a solid immunity to prevent the assault of potentially deadly …

Human cytomegalovirus glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB …

CS Nelson, JA Jenks, N Pardi, M Goodwin… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT A vaccine to prevent maternal acquisition of human cytomegalovirus (HCMV)
during pregnancy is a primary strategy to reduce the incidence of congenital disease. The …