Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) resulting in dopamine …

Neuroinflammation, an inflammatory response within the central nervous system (CNS), is a
main hallmark of common neurodegenerative diseases, including Alzheimer's disease (AD) …

Parkinson's disease (PD) is a debilitating neurological disorder characterized by the
impairment of the motor system, resulting in symptoms such as resting tremor, cogwheel …

Treatment of neurodegenerative diseases has become one of the most challenging topics of
the last decades due to their prevalence and increasing societal cost. The crucial point of the …

Even though Parkinson's disease (PD) is the second most common neurological disorder
(ND), it faces an absence of credible drug delivery, treatment and diagnosis. Levodopa is …

In view of the fact that the blood–brain barrier (BBB) prevents the transport of imaging
probes and therapeutic agents to the brain and thus hinders the diagnosis and treatment of …

Parkinson's disease (PD) significantly affects patients' quality of life and represents a high
economic burden for health systems. Given the lack of safe and effective treatments for PD …

Parkinson's disease (PD) is a chronic, and highly neurodegenerative disorder with complex
pathological processes. The features for neuropathological identification of PD include α …

Tunneling nanotubes (TNTs), discovered in 2004, are thin, long protrusions between cells
utilized for intercellular transfer and communication. These newly discovered structures …

Protein homeostasis, or proteostasis, is essential for cell function and viability. Unwanted,
damaged, misfolded and aggregated proteins are degraded by the ubiquitin–proteasome …