Targeted therapy for hepatocellular carcinoma: old and new opportunities

C Laface, P Fedele, FM Maselli, F Ambrogio, C Foti… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the most frequent primitive cancer of
the liver, accounting for 90% of all recorded cases. HCC is the third most common cause of …

Current state of liver-directed therapies and combinatory approaches with systemic therapy in hepatocellular carcinoma (HCC)

P Viveiros, A Riaz, RJ Lewandowski, D Mahalingam - Cancers, 2019 - mdpi.com
The increasing set of liver-directed therapies (LDT) have become an integral part of
hepatocellular carcinoma (HCC) treatment. These range from percutaneous ablative …

Immunotherapy and the combination with targeted therapies for advanced hepatocellular carcinoma

C Laface, G Ranieri, FM Maselli, F Ambrogio, C Foti… - Cancers, 2023 - mdpi.com
Simple Summary One of the most important abilities of a tumor is to establish a state of
immunosuppression inside the tumor microenvironment. This is made possible through …

Drug-eluting embolic microspheres for local drug delivery–State of the art

K Fuchs, R Duran, A Denys, PE Bize… - Journal of Controlled …, 2017 - Elsevier
Embolic microspheres or beads used in transarterial chemoembolization are an established
treatment method for hepatocellular carcinoma patients. The occlusion of the tumor-feeding …

Hepatic arterial infusion of chemotherapy for advanced hepatobiliary cancers: state of the art

C Laface, M Laforgia, P Molinari, I Ugenti, CD Gadaleta… - Cancers, 2021 - mdpi.com
Simple Summary Liver functional failure is one of the leading causes of cancer-related
death. Systemic chemotherapy usually offers a modest benefit in terms of disease control …

Using traditional Chinese medicine to treat hepatocellular carcinoma by targeting tumor immunity

W Jia, L Wang - Evidence‐Based Complementary and …, 2020 - Wiley Online Library
As the leading cause of cancer‐related death, hepatocellular carcinoma (HCC) threatens
human health and limited treatments are available to cure the disease efficiently and …

[HTML][HTML] Vascular endothelial growth factor and tryptase changes after chemoembolization in hepatocarcinoma patients

G Ranieri, M Ammendola, I Marech… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To evaluate vascular endothelial growth factor (VEGF) and tryptase in hepatocellular
cancer (HCC) before and after trans-arterial chemoembolization (TACE). METHODS: VEGF …

[HTML][HTML] Immunomodulation in hepatocellular cancer

S Lee, M Loecher, R Iyer - Journal of gastrointestinal oncology, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fastest growing malignancy in the United States in
relation to mortality. HCC relies on a complex immunosuppressive network to modify the …

Loco-Regional and Systemic Chemotherapies for Hepato-Pancreatic Tumors: Integrated Treatments

G Ranieri, C Laface - Cancers, 2020 - mdpi.com
This Special Issue of Cancers, titled “Loco-Regional Arterial Chemotherapies Alone or in
Combination with Systemic Treatments for Primary and Secondary Hepato-Pancreatic …

Comparative efficacy and safety of molecular targeted agents combined with transarterial chemoembolization in the treatment of unresectable hepatocellular …

J Long, B Chen, Z Liu - Frontiers in Oncology, 2023 - frontiersin.org
Objective: At present, several molecular targeted agents (MTAs) combined with transarterial
chemoembolization (TACE) have been employed to treat unresectable hepatocellular …