Effects of different storage solutions on renal ischemia tolerance after kidney transplantation in mice

L Wang, J Wei, S Jiang, HH Li, L Fu… - American Journal of …, 2018 - journals.physiology.org
storage is the most prevalent method for graft preservation in kidney transplantation (KTX).
The protective effects of various preservation solutions have been studied extensively in …

Normothermic ex-vivo liver perfusion: where do we stand and where to reach?

K Jayant, I Reccia, AMJ Shapiro - Expert review of …, 2018 - Taylor & Francis
Introduction: Nowadays liver transplantation is considered as the treatment of choice,
however, the scarcity of suitable donor organs limits the delivery of care to the end-stage …

PARP inhibition attenuates histopathological lesion in ischemia/reperfusion renal mouse model after cold prolonged ischemia

RMG del Moral, M Gómez-Morales… - The Scientific World …, 2013 - Wiley Online Library
We test the hypothesis that PARP inhibition can decrease acute tubular necrosis (ATN) and
other renal lesions related to prolonged cold ischemia/reperfusion (IR) in kidneys preserved …

Melatonin role preventing steatohepatitis and improving liver transplantation results

E Esteban-Zubero, FA García-Gil… - Cellular and Molecular …, 2016 - Springer
Liver steatosis is a prevalent process that is induced due to alcoholic or non-alcoholic
intake. During the course of these diseases, the generation of reactive oxygen species …

An improved rapid sampling microdialysis system for human and porcine organ monitoring in a hospital setting

SAN Gowers, K Hamaoui, N Vallant, GB Hanna… - Analytical …, 2018 - pubs.rsc.org
Online organ monitoring could provide clinicians with critical information regarding organ
health prior to transplantation and could aid clinical decision-making. This paper presents …

[HTML][HTML] Metabolic shift in liver: correlation between perfusion temperature and hypoxia inducible factor-1α

A Ferrigno, LG Di Pasqua, A Bianchi… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To study at what temperature the oxygen carried by the perfusate meets liver
requirements in a model of organ perfusion. METHODS: In this study, we correlated hypoxia …

Identifying risk factors in renal allografts before transplant: machine-measured renal resistance and posttransplant allograft survival

YY Yushkov, J Stern, A Ying, N Icitovic… - Progress in …, 2012 - journals.sagepub.com
Enhancement of renal allograft function and survival in an era where expanded criteria
donors are increasingly used requires validated selection criteria. The goal of this …

UW is superior compared with HTK after prolonged preservation of renal grafts

S Hoeger, G Lueg, C Tsagogiorgas… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: In recent clinical studies, the efficacy of histidine-tryptophan-ketoglutarate
(HTK) in kidney transplantation was questioned. This study compares the efficacy of …

Hypothermic kidney preservation: a remembrance of the past in the future?

MO Timsit, SG Tullius - Current Opinion in Organ Transplantation, 2011 - journals.lww.com
Organ preservation is a critical aspect for the overall success in organ transplantation. The
current increased utilization of reduced quality kidneys will require us to further improve our …

[HTML][HTML] Enhancing Liver Transplant Outcomes through Liver Precooling to Mitigate Inflammatory Response and Protect Mitochondrial Function

MH Tran, J Gao, X Wang, R Liu, CL Parris, C Esquivel… - Biomedicines, 2024 - mdpi.com
Transplanted organs experience several episodes of ischemia and ischemia-reperfusion.
The graft injury resulting from ischemia-reperfusion (IRI) remains a significant obstacle to the …