Epigenetic alterations in the gastrointestinal tract: current and emerging use for biomarkers of cancer

WM Grady - Advances in cancer research, 2021 - Elsevier
Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

Regulatory roles of non-coding RNAs in colorectal cancer

J Wang, YX Song, B Ma, JJ Wang, JX Sun… - International journal of …, 2015 - mdpi.com
Non-coding RNAs (ncRNAs) have recently gained attention because of their involvement in
different biological processes. An increasing number of studies have demonstrated that …

miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1

M Zeng, L Zhu, L Li, C Kang - Cellular & Molecular Biology Letters, 2017 - Springer
Background MicroRNAs (miRNAs) play important roles in the growth and metastasis of
colon cancer. It is known that one set of miRNAs are dysregulated in colon cancer cells, but …

The circular RNA 001971/miR-29c-3p axis modulates colorectal cancer growth, metastasis, and angiogenesis through VEGFA

C Chen, Z Huang, X Mo, Y Song, X Li, X Li… - Journal of Experimental & …, 2020 - Springer
Background Colorectal cancer (CRC) is one of the most common malignant tumors globally.
Angiogenesis is a key event maintaining tumor cell survival and aggressiveness. The …

miR-21 promotes EGF-induced pancreatic cancer cell proliferation by targeting Spry2

Q Zhao, S Chen, Z Zhu, L Yu, Y Ren, M Jiang… - Cell Death & …, 2018 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant cancer that lacks effective
targets for therapy. Alteration of epidermal growth factor (EGF) expression has been …

The co‐regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer

ML Slattery, JS Herrick, LE Mullany… - Genes …, 2017 - Wiley Online Library
Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis.
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …

[HTML][HTML] Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively

J Chen, Y Xia, X Sui, Q Peng, T Zhang, J Li, J Zhang - Oncotarget, 2018 - ncbi.nlm.nih.gov
New anticancer agents with lower toxicity have been always urged because of drug
resistance associated with overused chemotherapy agents. In this study, steviol, a colonic …

Comprehensive analysis of competitive endogenous RNAs network associated with head and neck squamous cell carcinoma

XN Fang, M Yin, H Li, C Liang, C Xu, GW Yang… - Scientific Reports, 2018 - nature.com
Long non-coding RNAs (lncRNAs) can regulate gene expression directly or indirectly
through interacting with microRNAs (miRNAs). However, the role of differentially expressed …

[HTML][HTML] Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle-invasive bladder cancer

H Wang, L Niu, S Jiang, J Zhai, P Wang, F Kong, X Jin - Oncotarget, 2016 - ncbi.nlm.nih.gov
Although initially thought to be transcriptional noise, long noncoding RNAs (lncRNAs) are
gaining increased attention in human cancers as its diversity function. At present, lncRNAs …

Role of microRNAs in the resistance of colorectal cancer to chemoradiotherapy

QB Wu, X Sheng, N Zhang… - Molecular and …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is among the main tumor-related causes of death worldwide. The
fact that the majority of the patients develop resistance to chemoradiotherapy (CRT) is a …