[HTML][HTML] Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges

A Kumar, B BharathwajChetty, MK Manickasamy… - Pharmacological …, 2024 - Elsevier
Cancer has become a burgeoning global healthcare concern marked by its exponential
growth and significant economic ramifications. Though advancements in the treatment …

[HTML][HTML] Targeting PI3K/AKT/mTOR and MAPK Signaling Pathways in Gastric Cancer

DT Morgos, C Stefani, D Miricescu, M Greabu… - International Journal of …, 2024 - mdpi.com
Gastric cancer (GC) is the fourth leading cause of death worldwide, with more than 1 million
cases diagnosed every year. Helicobacter pylori represents the main risk factor, being …

[HTML][HTML] An international Delphi consensus for surgical quality assessment of lymphadenectomy and anastomosis in minimally invasive total gastrectomy for gastric …

A Cizmic, I Romic, A Balla, N Barabino, G Anania… - Surgical …, 2024 - Springer
Background Minimally invasive total gastrectomy (MITG) is a mainstay for curative treatment
of patients with gastric cancer. To define and standardize optimal surgical techniques and …

Development and verification of a manganese metabolism-and immune-related genes signature for prediction of prognosis and immune landscape in gastric cancer

X Han, C Leng, S Zhao, S Wang, S Chen… - Frontiers in …, 2024 - frontiersin.org
Background Gastric cancer (GC) poses a global health challenge due to its widespread
prevalence and unfavorable prognosis. Although immunotherapy has shown promise in …

[HTML][HTML] Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the …

A Khan, Y Waheed, S Kuttikrishnan… - Frontiers in …, 2024 - frontiersin.org
In the current study, Neosetophomone B (NSP–B) was investigated for its anti-cancerous
potential using network pharmacology, quantum polarized ligand docking, molecular …

[HTML][HTML] ARID1A Mutations in Gastric Cancer: A Review with Focus on Clinicopathological Features, Molecular Background and Diagnostic Interpretation

G Angelico, G Attanasio, L Colarossi, C Colarossi… - Cancers, 2024 - mdpi.com
Simple Summary ARID1A mutations are emerging as a prognostic and predictive factor in
gastric cancer. Recent studies suggest their potential role in predicting patient response to …

A weighted distance-based dynamic ensemble regression framework for gastric cancer survival time prediction

L Xu, C Guo, M Liu - Artificial Intelligence in Medicine, 2024 - Elsevier
Accurate prediction of gastric cancer patient survival time is essential for clinical decision-
making. However, unified static models lack specificity and flexibility in predictions owing to …

Targeting cellular senescence as a therapeutic vulnerability in gastric cancer

H Geng, C Huang, L Xu, Y Zhou, Z Dong, Y Zhong, Q Li… - Life Sciences, 2024 - Elsevier
Aims Cellular senescence (CS) represents an intracellular defense mechanism responding
to stress signals and can be leveraged as a “vulnerability” in cancer treatment. This study …

[HTML][HTML] Beef peptides mitigate skeletal muscle atrophy in C2C12 myotubes through protein degradation, protein synthesis, and the oxidative stress pathway

H Hur, HJ Kim, D Lee, C Jo - Food & Function, 2024 - pubs.rsc.org
This study aimed to investigate the potential of beef peptides (BPs) in mitigating muscle
atrophy induced by dexamethasone (DEX) with underlying three mechanisms in vitro …

Ultrasound-Assisted Extraction of Atractylodes chinensis (DC.) Koidz. Polysaccharides and the Synergistic Antigastric Cancer Effect in Combination with Oxaliplatin

M Liang, Y Wu, J Sun, Y Zhao, L Liu, R Zhao… - ACS …, 2024 - ACS Publications
Oxaliplatin (OXA) is recognized as a first-line drug for gastric cancer. However, low
accumulation of the OXA in the target site and the development of drug resistance directly …