Effects of prenatal opioid exposure on synaptic adaptations and behaviors across development

SC Simmons, GG Grecco, BK Atwood, FS Nugent - Neuropharmacology, 2023 - Elsevier
In this review, we focus on prenatal opioid exposure (POE) given the significant concern for
the mental health outcomes of children with parents affected by opioid use disorder (OUD) in …

Sex differences in the rodent hippocampal opioid system following stress and oxycodone associated learning processes

J Chalangal, S Mazid, K Windisch, TA Milner - … Biochemistry and Behavior, 2022 - Elsevier
Over the past two decades, opioid abuse has risen especially among women. In both sexes
hippocampal neural circuits involved in associative memory formation and encoding of …

Detection of vaping, cannabis use, and hazardous prescription opioid use among adolescents

GF Dash, L Holt, EA Kenyon, EK Carter… - The Lancet Child & …, 2022 - thelancet.com
There has been a global surge in adolescents' use of electronic nicotine delivery systems
(vaping), cannabis (vaped and edible), and prescription opioids, collectively termed ECPO …

Opioids and youth athletes

HJ Benjamin, MM Perri, J Leemputte… - Sports …, 2024 - journals.sagepub.com
Context: The ongoing opioid epidemic and associated adverse effects impart a large burden
on our current healthcare system. The annual economic and noneconomic cost of opioid …

Early life adversity: Epigenetic regulation underlying drug addiction susceptibility

JJ Winter, KL Rodríguez-Acevedo, M Dittrich… - Molecular and Cellular …, 2023 - Elsevier
Drug addiction is a leading cause of disability worldwide, with more than 70,000 Americans
dying from drug overdose in 2019 alone. While only a small percentage of chronic drug …

Association between psychopathological symptoms and aggression and selected biochemical parameters in adolescents with behavioural and emotional …

M Śmiarowska, M Pawlicka, A Boroń… - International journal of …, 2023 - mdpi.com
Behavioural and emotional disturbances (F92. 8) are the most recognized disorders in a
developmental psychiatry. As the problem is still alarmingly increasing, the searches for their …

Cannabidiol Protects against the Reinstatement of Oxycodone-Induced Conditioned Place Preference in Adolescent Male but Not Female Rats: The Role of MOR and …

J Socha, P Grochecki, M Marszalek-Grabska… - International Journal of …, 2024 - mdpi.com
Cannabidiol (CBD), a phytocannabinoid, appeared to satisfy several criteria for a safe
approach to preventing drug-taking behavior, including opioids. However, most successful …

Psychotherapies in opioid use disorder: toward a step-care model

A Durpoix, J Rolling, R Coutelle, L Lalanne - Journal of neural …, 2024 - Springer
Opioid use disorder (OUD) is characterized by a lack of control in opioid use, resulting in
psychological distress and deficits in interpersonal and social functioning. OUD is often …

Sex differences in sensitivity to fentanyl effects in mice: Behavioral and molecular findings during late adolescence

É Kestering-Ferreira, BA Heberle, F Lummertz… - Neuroscience …, 2024 - Elsevier
Purpose Sex differences play a crucial role in understanding vulnerability to opioid
addiction, yet there have been limited preclinical investigations of this effect during the …

Incubation of oxycodone craving following adult-onset and adolescent-onset oxycodone self-Administration in Male Rats

RD Altshuler, KT Garcia, X Li - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
Relapse is a major obstacle to curb the ongoing epidemic of prescription opioid abuse. We
and others previously demonstrated that oxycodone seeking in adult rats progressively …