Smooth muscles are complex tissues containing a variety of cells in addition to muscle cells.
Interstitial cells of mesenchymal origin interact with and form electrical connectivity with …

In electrically nonexcitable cells, Ca2+ influx is essential for regulating a host of kinetically
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …

The vascular myogenic response refers to the acute reaction of a blood vessel to a change
in transmural pressure. This response is critically important for the development of resting …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents,
both autonomic and somatic, and supraspinal influences from visual, olfactory, and …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but
also by visual, olfactory, and imaginary stimuli. The reflex involves both autonomic and …

The Drosophila transient receptor potential protein (TRP) and its mammalian homologues
are thought to be Ca2+-permeable cation channels activated by G protein (Gq/11)–coupled …

Sustained elevation in the intracellular Ca2+ concentration via Ca2+ influx, which is
activated by a variety of mechanisms, plays a central regulatory role for cardiovascular …

PURPOSE: The importance of signaling pathways in penile smooth muscles involved in
normal erection and erectile dysfunction (ED) is discussed based on a review of the …

All current smooth muscle cell (SMC) Cre mice similarly recombine floxed alleles in vascular
and visceral SMCs. Here we present an Itga8-CreER T2 knock-in mouse and compare its …

The enteric nervous system regulates intestinal motility. It contains intrinsic sensory
neurones, several types of interneurones and excitatory and inhibitory motor neurones. This …