The incidence of esophageal adenocarcinoma (EAC) has increased in many Western
countries and is higher in men than women. Some risk factors for EAC have been identified …

Esophageal cancer (EsC) is one of the least studied and deadliest cancers worldwide
because of its extremely aggressive nature and poor survival rate. It ranks sixth among all …

Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in Western cultures.
Barrett's esophagus is the presumed precursor lesion for this cancer. Several other risk …

Obesity usually is associated with morbidity related to diabetes mellitus and cardiovascular
diseases. However, there are many gastrointestinal and hepatic diseases for which obesity …

Esophageal cancer is a deadly disease, ranking sixth among all cancers in mortality.
Despite incremental advances in diagnostics and therapeutics, esophageal cancer still …

The worldwide incidence of GORD and its complications is increasing along with the
exponentially increasing problem of obesity. Of particular concern is the relationship …

Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …

Background & Aims Barrett's esophagus (BE) is a precursor to esophageal adenocarcinoma
(EAC). Progression from BE to cancer is associated with obesity, possibly due to increased …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and
associated disorders, including gastrointestinal cancers, have high morbidity and mortality …