BOB CAT: a large-scale review and Delphi consensus for management of Barrett's esophagus with no dysplasia, indefinite for, or low-grade dysplasia

C Bennett, P Moayyedi, DA Corley… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Barrett's esophagus (BE) is a common premalignant lesion for which
surveillance is recommended. This strategy is limited by considerable variations in clinical …

Precision prevention of oesophageal adenocarcinoma

TL Vaughan, RC Fitzgerald - Nature reviews Gastroenterology & …, 2015 - nature.com
The incidence of oesophageal adenocarcinoma has risen rapidly over the past four
decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a …

Insulin and cancer: a tangled web

BP Leitner, S Siebel, ND Akingbesote… - Biochemical …, 2022 - portlandpress.com
For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …

Obesity and esophageal cancer: GERD, Barrett s esophagus, and molecular carcinogenic pathways

F Schlottmann, NH Dreifuss, MG Patti - Expert review of …, 2020 - Taylor & Francis
Introduction Increases in the rates of esophageal adenocarcinoma (EAC) have paralleled
rises in the prevalence of overweight and obesity. Despite not being fully understood …

[HTML][HTML] Obesity-related digestive diseases and their pathophysiology

SY Nam - Gut and liver, 2017 - ncbi.nlm.nih.gov
Obesity is a growing medical and public health problem worldwide. Many digestive diseases
are related to obesity. In this article, the current state of our knowledge of obesity-related …

[HTML][HTML] Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus

C Palles, L Chegwidden, X Li, JM Findlay, G Farnham… - Gastroenterology, 2015 - Elsevier
Background & Aims Barrett's esophagus (BE) increases the risk of esophageal
adenocarcinoma (EAC). We found the risk to be BE has been associated with single …

Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies

X Du, K Hidayat, BM Shi - Bioscience reports, 2017 - portlandpress.com
To systematically and quantitatively review the relation of abdominal obesity, as measured
by waist circumference (WC) and waist to hip ratio (WHR), to total gastroesophageal cancer …

[HTML][HTML] Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective study of 580 000 subjects within the Me-Can project

B Lindkvist, D Johansen, T Stocks, H Concin, T Bjørge… - BMC cancer, 2014 - Springer
Background Obesity is associated with an increased risk of esophageal adenocarcinoma
(EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However …

The tumour immune microenvironment in oesophageal cancer

M Davern, NE Donlon, R Power, C Hayes… - British Journal of …, 2021 - nature.com
Oesophageal cancer (OC) is an inflammation-associated malignancy linked to gastro-
oesophageal reflux disease, obesity and tobacco use. Knowledge of the microenvironment …

Circulating inflammatory cytokines and adipokines are associated with increased risk of Barrett's esophagus: a case–control study

JM Garcia, AE Splenser, J Kramer, A Alsarraj… - Clinical …, 2014 - Elsevier
Background & Aims Obesity is associated with Barrett's esophagus (BE) and with changes in
circulating levels of adipokines (leptin and adiponectin) and cytokines. Although studies …