DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

E Hannon, EL Dempster, G Mansell, J Burrage, N Bass… - Elife, 2021 - elifesciences.org
We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …

Autism spectrum disorder and schizophrenia: An updated conceptual review

A Jutla, J Foss‐Feig… - Autism …, 2022 - Wiley Online Library
Autism spectrum disorder (ASD) and schizophrenia (SCZ) are separate disorders, with
distinct clinical profiles and natural histories. ASD, typically diagnosed in childhood, is …

Polygenic risk score, parental socioeconomic status, family history of psychiatric disorders, and the risk for schizophrenia: a Danish population-based study and meta …

E Agerbo, PF Sullivan, BJ Vilhjalmsson… - JAMA …, 2015 - jamanetwork.com
Importance Schizophrenia has a complex etiology influenced both by genetic and
nongenetic factors but disentangling these factors is difficult. Objective To estimate (1) how …

Top 10 replicated findings from behavioral genetics

R Plomin, JC DeFries, VS Knopik… - Perspectives on …, 2016 - journals.sagepub.com
In the context of current concerns about replication in psychological science, we describe 10
findings from behavioral genetic research that have replicated robustly. These are “big” …

The neurodevelopmental hypothesis of schizophrenia, revisited

SH Fatemi, TD Folsom - Schizophrenia bulletin, 2009 - academic.oup.com
While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …

Schizophrenia and migration: a meta-analysis and review

E Cantor-Graae, JP Selten - American journal of psychiatry, 2005 - Am Psychiatric Assoc
OBJECTIVE: The authors synthesize findings of previous studies implicating migration as a
risk factor for the development of schizophrenia and provide a quantitative index of the …

[HTML][HTML] Molecular mechanisms of schizophrenia: Insights from human genetics

Z Farsi, M Sheng - Current Opinion in Neurobiology, 2023 - Elsevier
Schizophrenia is a debilitating psychiatric disorder that affects millions of people worldwide;
however, its etiology is poorly understood at the molecular and neurobiological levels. A …

[HTML][HTML] The impact of environmental factors in severe psychiatric disorders

A Schmitt, B Malchow, A Hasan, P Falkai - Frontiers in neuroscience, 2014 - frontiersin.org
During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

PJ Harrison, DR Weinberger - Molecular psychiatry, 2005 - nature.com
This review critically summarizes the neuropathology and genetics of schizophrenia, the
relationship between them, and speculates on their functional convergence. The …

[图书][B] The handbook of child and adolescent clinical psychology: A contextual approach

A Carr - 2015 - taylorfrancis.com
The third edition of the hugely successful Handbook of Child and Adolescent Clinical
Psychology incorporates important advances in the field to provide a reliable and accessible …