Background and purpose Diffusion weighted imaging (DWI) allows for the interrogation of
tissue cellularity, which is a surrogate for cellular proliferation. Previous attempts to …

Simple Summary Patients diagnosed with pancreatic cancer have very few treatment
options. In order to identify new treatment opportunities, and develop new drugs for clinical …

Peroxisome proliferator-activated receptor delta (PPARD) is a nuclear receptor known to
play an essential role in regulation of cell metabolism, cell proliferation, inflammation, and …

Untargeted Nuclear Magnetic Resonance (NMR) metabolomics of polar extracts from the
pancreata of a caerulin-induced mouse model of pancreatitis (Pt) and of a transgenic mouse …

Pancreatic ductal adenocarcinoma (PDAC) is considered one most aggressive and lethal
cancer types worldwide. While its underlying mechanisms are still poorly understood …

Hyperpolarized 13C nuclear magnetic resonance spectroscopy can characterize in vivo
tissue metabolism, including preclinical models of cancer and inflammatory disease. Broad …

While pancreatic cancer (PC) survival rates have recently shown modest improvement, the
disease remains largely incurable. Early detection of pancreatic cancer may result in …

This review article discusses the potential of hyperpolarized (HP) 13C magnetic resonance
spectroscopic imaging (MRSI) as a noninvasive technique for identifying altered metabolism …

Rapid diagnosis and therapeutic monitoring of aggressive diseases such as glioblastoma
can improve patient survival by providing physicians the time to optimally deliver treatment …

This study explored the usefulness of multiple quantitative MRI approaches to detect
pancreatic ductal adenocarcinomas in two murine models, PAN‐02 and KPC. Methods …