Shared TIR enzymatic functions regulate cell death and immunity across the tree of life

K Essuman, J Milbrandt, JL Dangl, MT Nishimura - Science, 2022 - science.org
In the 20th century, researchers studying animal and plant signaling pathways discovered a
protein domain that is shared across diverse innate immune systems: the Toll/interleukin …

Action mechanisms of effectors in plant-pathogen interaction

S Zhang, C Li, J Si, Z Han, D Chen - International Journal of Molecular …, 2022 - mdpi.com
Plant pathogens are one of the main factors hindering the breeding of cash crops.
Pathogens, including oomycetes, fungus, and bacteria, secrete effectors as invasion …

Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity

S Huang, A Jia, W Song, G Hessler, Y Meng, Y Sun… - Science, 2022 - science.org
Plant nucleotide-binding leucine-rich repeat-containing (NLR) receptors with an N-terminal
Toll/interleukin-1 receptor (TIR) domain sense pathogen effectors to enable TIR-encoded …

TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity

A Jia, S Huang, W Song, J Wang, Y Meng, Y Sun, L Xu… - Science, 2022 - science.org
Plant pathogen–activated immune signaling by nucleotide-binding leucine-rich repeat
(NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain converges on …

Effector‐dependent activation and oligomerization of plant NRC class helper NLRs by sensor NLR immune receptors Rpi‐amr3 and Rpi‐amr1

HK Ahn, X Lin, AC Olave‐Achury, L Derevnina… - The EMBO …, 2023 - embopress.org
Plant pathogens compromise crop yields. Plants have evolved robust innate immunity that
depends in part on intracellular Nucleotide‐binding, Leucine rich‐Repeat (NLR) immune …

Sensor NLR immune proteins activate oligomerization of their NRC helpers in response to plant pathogens

MP Contreras, H Pai, Y Tumtas, C Duggan… - The EMBO …, 2023 - embopress.org
Nucleotide‐binding domain leucine‐rich repeat (NLR) immune receptors are important
components of plant and metazoan innate immunity that can function as individual units or …

Salicylic acid and jasmonic acid crosstalk in plant immunity

S Hou, K Tsuda - Essays in Biochemistry, 2022 - portlandpress.com
The phytohormones salicylic acid (SA) and jasmonic acid (JA) are major players in plant
immunity. Numerous studies have provided evidence that SA-and JA-mediated signaling …

Oligomerization of a plant helper NLR requires cell-surface and intracellular immune receptor activation

JM Feehan, J Wang, X Sun, J Choi… - Proceedings of the …, 2023 - National Acad Sciences
Plant disease resistance involves both detection of microbial molecular patterns by cell-
surface pattern recognition receptors and detection of pathogen effectors by intracellular …

[PDF][PDF] Cell-type-specific responses to fungal infection in plants revealed by single-cell transcriptomics

B Tang, L Feng, MT Hulin, P Ding, W Ma - Cell Host & Microbe, 2023 - cell.com
Pathogen infection is a dynamic process. Here, we employ single-cell transcriptomics to
investigate plant response heterogeneity. By generating an Arabidopsis thaliana leaf atlas …

A detailed landscape of CRISPR-Cas-mediated plant disease and pest management

S Karmakar, P Das, D Panda, K Xie, MJ Baig, KA Molla - Plant Science, 2022 - Elsevier
Genome editing technology has rapidly evolved to knock-out genes, create targeted genetic
variation, install precise insertion/deletion and single nucleotide changes, and perform large …