Immunotherapy and targeted therapy for cervical cancer: an update

G Menderes, J Black, CL Schwab… - Expert review of …, 2016 - Taylor & Francis
The prognosis of patients with metastatic cervical cancer is poor with a median survival of 8–
13 months. Despite the potency of chemotherapeutic drugs, this treatment is rarely curative …

[HTML][HTML] Be active or not: the relative contribution of active and passive tumor targeting of nanomaterials

R Li, K Zheng, C Yuan, Z Chen, M Huang - Nanotheranostics, 2017 - ncbi.nlm.nih.gov
Malignant tumor (cancer) remains as one of the deadliest diseases throughout the world,
despite its overall mortality drops. Nanomaterials (NMs) have been widely studied as …

Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells

N Eckstein, K Servan, B Hildebrandt, A Pölitz… - Cancer research, 2009 - AACR
Platinum plays a central role in the therapy of ovarian cancer, and the emergence of
platinum resistance is a major obstacle for clinical management of the disease. We treated …

Growth factors controlling ovarian functions

AV Sirotkin - Journal of cellular physiology, 2011 - Wiley Online Library
The present review demonstrates an important role of different growth factors (of insulin‐like
growth factors, epidermal growth factors, vascular endothelial growth factor, thrombopoietin …

[HTML][HTML] AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers

H Lemjabbar-Alaoui, CJ Peto, YW Yang… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Poly (ADP-ribose) polymerase (PARP) has recently emerged as a central mediator
in cancer resistance against numerous anticancer agents to include chemotherapeutic …

Potential applications of nanoparticles for tumor microenvironment remodeling to ameliorate cancer immunotherapy

Y Bai, Y Wang, X Zhang, J Fu, X Xing, C Wang… - International Journal of …, 2019 - Elsevier
In recent years, researchers have made significant innovations in the field of tumor
immunotherapy based on the knowledge of biology, oncology, and immunology. Tumor …

Hyaluronic acid–paclitaxel: Effects of intraperitoneal administration against CD44 (+) human ovarian cancer xenografts

I De Stefano, A Battaglia, GF Zannoni… - Cancer chemotherapy …, 2011 - Springer
Abstract Purpose Hyaluronan (HA)-receptors (mainly CD44 and RHAMM) are
overexpressed in a wide variety of cancers including ovarian tumors, and HA-bioconjugates …

Deacetylated Sialic Acid Sensitizes Lung and Colon Cancers to Novel Cucurbitacin-Inspired Estrone Epidermal Growth Factor Receptor (EGFR) Inhibitor Analogs

MT Anim, I Tuffour, R Willis, M Schell, T Ostlund… - Molecules, 2023 - mdpi.com
Cancers utilize sugar residues such as sialic acids (Sia) to improve their ability to survive.
Sia presents a variety of functional group alterations, including O-acetylation on the C6 …

EGF-receptor regulation of matrix metalloproteinases in epithelial ovarian carcinoma

LG Hudson, NM Moss, MS Stack - 2009 - Taylor & Francis
Ovarian carcinoma is most frequently detected when disease has already disseminated intra-
abdominally, resulting in a 5-year survival rate of less than 20% owing to complications of …

Quantitative determination of antidepressants and their select degradates by liquid chromatography/electrospray ionization tandem mass spectrometry in biosolids …

LM Niemi, KA Stencel, MJ Murphy… - Analytical …, 2013 - ACS Publications
Antidepressants are one of the most widely dispensed classes of pharmaceuticals in the
United States. As wastewater treatment plants are a primary source of pharmaceuticals in …