[HTML][HTML] There is urgent need to treat atherosclerotic cardiovascular disease risk earlier, more intensively, and with greater precision: A review of current practice and …

ME Makover, MD Shapiro, PP Toth - American Journal of Preventive …, 2022 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is
etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke …

Accelerated vascular aging in chronic kidney disease: the potential for novel therapies

S Hobson, S Arefin, A Witasp, L Hernandez… - Circulation …, 2023 - Am Heart Assoc
The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Immune system dysfunction and inflammation in hemodialysis patients: two sides of the same coin

S Campo, A Lacquaniti, D Trombetta… - Journal of Clinical …, 2022 - mdpi.com
Biocompatibility in hemodialysis (HD) has considerably improved in recent decades, but
remains an open issue to be solved, appearing essential to reduce systemic inflammation …

Chronic kidney disease as a comorbidity in heart failure

M Szlagor, J Dybiec, E Młynarska, J Rysz… - International Journal of …, 2023 - mdpi.com
Heart failure (HF) is one of the greatest problems in healthcare and it often coexists with
declining renal function. The pathophysiology between the heart and the kidneys is …

[HTML][HTML] Hypertension in chronic kidney disease: What lies behind the scene

OZ Ameer - Frontiers in pharmacology, 2022 - frontiersin.org
Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The association between weight-adjusted-waist index and abdominal aortic calcification in adults aged≥ 40 years: results from NHANES 2013–2014

Z Qin, D Du, Y Li, K Chang, Q Yang, Z Zhang, R Liao… - Scientific Reports, 2022 - nature.com
The negative effects of obesity on the cardiovascular health have drawn much attention.
Weight-adjusted-waist index (WWI) has been proved to reflect weight-independent …

[HTML][HTML] Targeting HMGB1: A potential therapeutic strategy for chronic kidney disease

T Liu, Q Li, Q Jin, L Yang, H Mao, P Qu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
High-mobility group protein box 1 (HMGB1) is a member of a highly conserved high-mobility
group protein present in all cell types. HMGB1 plays multiple roles both inside and outside …

[HTML][HTML] Inflammation and cardiovascular disease associated with hemodialysis for end-stage renal disease

Y Wang, L Gao - Frontiers in Pharmacology, 2022 - frontiersin.org
Chronic kidney disease (CKD) and cardiac insufficiency often co-exist, particularly in uremic
patients on hemodialysis (HD). The occurrence of abnormal renal function in patients with …

Statins in Chronic Kidney Disease—Effects on Atherosclerosis and Cellular Senescence

P Fularski, J Krzemińska, N Lewandowska… - Cells, 2023 - mdpi.com
Chronic kidney disease (CKD) is a serious health problem that can affect various systems in
the human body. Renal failure promotes mechanisms of premature cellular aging and also …

The innate immune system in human kidney inflammaging

V Sepe, C Libetta, M Gregorini, T Rampino - Journal of nephrology, 2022 - Springer
Elderly individuals with chronic disorders tend to develop inflammaging, a condition
associated with elevated levels of blood inflammatory markers, and increased susceptibility …