In recent years, enzymes have risen as promising therapeutic tools for different pathologies,
from metabolic deficiencies, such as fibrosis conditions, ocular pathologies or joint …

The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

The pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2) generated much interest on the basic pathogenetic mechanisms through which SARS …

It has been known for many years that the angiotensin-converting enzyme 2 (ACE2) is a cell
surface enzyme involved in the regulation of blood pressure. More recently, it was proven …

A damaged endothelium is an underlying condition of the many complications of COVID-19
patients. The increased mortality risk associated with diseases that have underlying …

The SARS-CoV-2 pandemic and the COVID-19 disease have affected everyone globally,
leading to one of recorded history's most significant research surges. As our knowledge …

The spread of coronavirus disease 2019 (COVID-19) throughout the world has resulted in
stressful healthcare burdens and global health crises. Developing an effective measure to …

Pulmonary fibrosis is a devastating lung disease with multifactorial etiology characterized by
alveolar injury, fibroblast proliferation and excessive deposition of extracellular matrix …

Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …

Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …