Chronic kidney disease: global dimension and perspectives

V Jha, G Garcia-Garcia, K Iseki, Z Li, S Naicker… - The Lancet, 2013 - thelancet.com
Chronic kidney disease is defined as a reduced glomerular filtration rate, increased urinary
albumin excretion, or both, and is an increasing public health issue. Prevalence is estimated …

Lancet Commission: Stem cells and regenerative medicine

G Cossu, M Birchall, T Brown, P De Coppi… - The Lancet, 2018 - thelancet.com
Executive summary In this Commission, we argue that a combination of poor quality science,
unclear funding models, unrealistic hopes, and unscrupulous private clinics threatens …

[HTML][HTML] Chronic kidney disease prediction based on machine learning algorithms

MA Islam, MZH Majumder, MA Hussein - Journal of pathology informatics, 2023 - Elsevier
Chronic kidney disease (CKD) is a dangerous ailment that can last a person's entire life and
is caused by either kidney malignancy or decreased kidney functioning. It is feasible to halt …

Early chronic kidney disease: diagnosis, management and models of care

OJ Wouters, DJ O'donoghue, J Ritchie… - Nature Reviews …, 2015 - nature.com
Chronic kidney disease (CKD) is prevalent in many countries, and the costs associated with
the care of patients with end-stage renal disease (ESRD) are estimated to exceed US $1 …

Epidemiology and mechanisms of uremia-related cardiovascular disease

M Tonelli, SA Karumanchi, R Thadhani - Circulation, 2016 - Am Heart Assoc
Patients with chronic kidney disease and end-stage renal disease are at 5-to 10-fold higher
risk for developing cardiovascular disease (CVD) than age-matched controls. Clinically …

[HTML][HTML] Executive summary for the 2015 annual data report of the China Kidney Disease Network (CK-NET)

F Wang, C Yang, J Long, X Zhao, W Tang, D Zhang… - Kidney International, 2019 - Elsevier
Chronic kidney disease (CKD) has received increased attention as a leading public health
problem worldwide. Globally surveillance systems for kidney disease are still lacking …

[HTML][HTML] Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation

CY Sun, SC Chang, MS Wu - Kidney international, 2012 - Elsevier
The expression of the renoprotective antiaging gene Klotho is decreased in uremia. Recent
studies suggest that Klotho may be a tumor suppressor, and its expression may be …

Chronic kidney disease in low-income to middle-income countries: the case for increased screening

C George, A Mogueo, I Okpechi… - BMJ global …, 2017 - gh.bmj.com
Chronic kidney disease (CKD) is fast becoming a major public health issue,
disproportionately burdening low-income to middle-income countries, where detection rates …

Curcumin ameliorates kidney function and oxidative stress in experimental chronic kidney disease

BH Ali, S Al‐Salam, Y Al Suleimani… - Basic & Clinical …, 2018 - Wiley Online Library
Chronic kidney disease (CKD) is known to involve inflammation, oxidative stress and
apoptosis. Here, we investigated the impact of curcumin (diferuloyl methane, a phenolic …

Pilot study of probiotic dietary supplementation for promoting healthy kidney function in patients with chronic kidney disease

N Ranganathan, P Ranganathan, EA Friedman… - Advances in …, 2010 - Springer
Introduction Uremic syndrome consists of nitrogenous waste retention, deficiency in kidney-
derived hormones, and reduced acid excretion, and, if untreated, may progress to coma and …