Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells,
strategically situated between the photoreceptors and the choroid, is the primary caretaker of …

Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

Mitochondria are energy factories of cells and are important pivots for intracellular
interactions with other organelles. They interact with the endoplasmic reticulum …

Abstract The Free Radical Theory of Ageing, was first proposed by Denham Harman in the
mid-1950's, based largely on work conducted by Rebeca Gerschman and Daniel Gilbert. At …

Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …

Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

Moringa oleifera is widely cultivated as an important vegetable for human consumption.
Moringa contains numerous dietary phytonutrients, including flavonoids, which are …