Objectives—Patients with obesity and diabetes mellitus have increased risk of
cardiovascular disease. A major cause is an atherogenic dyslipidemia related primarily to …

Background Patients with mild-to-moderate hypertriglyceridemia (HTG) are thought to share
specific genetic susceptibility factors that are also present in patients with severe HTG, but …

Background Lipoprotein lipase (LPL) is the key enzyme responsible for the hydrolysis of
triglycerides. Loss-of-function variants in the LPL gene are associated with …

Current Diagnosis and Management of Primary Chylomicronemia Page 1 883 J Atheroscler
Thromb, 2021; 28: 883-904. http://doi.org/10.5551/jat.RV17054 The official journal of the …

The continuous search for drugs targeting type 2 diabetes mellitus (T2DM) has led to the
identification of small molecules that disrupt the binding between glucokinase and …

The genetic screening program for familial hypercholesterolemia (FH) in the Netherlands,
which was embraced by the Dutch Ministry of Health from 1994 to 2014, has led to twenty …

Combined dyslipidemia (CD) is now the predominant dyslipidemic pattern in childhood,
characterized by moderate-to-severe elevation in triglycerides and non–high-density …

Background Monogenic hypertriglyceridemia (HTG) may result from mutations in some
genes which impair the intravascular lipolysis of triglyceride (TG)-rich lipoproteins mediated …

Disturbances in glucose and lipid homeostasis are cardinal features of the metabolic
syndrome that affect millions of people worldwide. These conditions have multi-organ …

The efficacy of Emblica officinalis extract (EOE) containing 10% β-glucogallin was compared
against metformin in newly diagnosed subjects with diabetic dyslipidemia which is a …