Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications

MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

[HTML][HTML] Polymeric micelles for breast cancer therapy: recent updates, clinical translation and regulatory considerations

V Junnuthula, P Kolimi, D Nyavanandi, S Sampathi… - Pharmaceutics, 2022 - mdpi.com
With the growing burden of cancer, parallel advancements in anticancer nanotechnological
solutions have been witnessed. Among the different types of cancers, breast cancer …

[HTML][HTML] Polysaccharide-based nanomedicines targeting lung cancer

AA Bhat, G Gupta, KS Alharbi, O Afzal, ASA Altamimi… - Pharmaceutics, 2022 - mdpi.com
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …

[HTML][HTML] The role of silver nanoparticles in the diagnosis and treatment of cancer: Are there any perspectives for the future?

P Takáč, R Michalková, M Čižmáriková, Z Bedlovičová… - Life, 2023 - mdpi.com
Cancer is a fatal disease with a complex pathophysiology. Lack of specificity and
cytotoxicity, as well as the multidrug resistance of traditional cancer chemotherapy, are the …

Bioresponsive drug delivery systems

SE Alavi, S Alharthi, SZ Alavi, A Raza… - Drug Discovery …, 2023 - Elsevier
In this review, we highlight the potential of stimuli-responsive drug delivery systems (DDSs)
to revolutionize healthcare. Through examining pH, temperature, enzyme, and redox …

Anticancer drug delivery by focused ultrasound-mediated blood-brain/tumor barrier disruption for glioma therapy: From benchside to bedside

C Bérard, C Truillet, B Larrat, F Dhermain… - Pharmacology & …, 2023 - Elsevier
The therapeutic management of gliomas remains particularly challenging. Brain tumors
present multiple obstacles that make therapeutic innovation complex, mainly due to the …

[HTML][HTML] Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug …

S Akash, S Bibi, P Biswas, N Mukerjee, DA Khan… - Frontiers in …, 2023 - frontiersin.org
Breast and lung cancer are two of the most lethal forms of cancer, responsible for a
disproportionately high number of deaths worldwide. Both doctors and cancer patients …

Synthesis and development of novel magnetic polymeric sorbent to simultaneous extraction of three anti-cancers using dispersive micro solid phase extraction …

A Saghafi, M Ghorbani, M Pakseresht, A Shams - Microchemical Journal, 2022 - Elsevier
A suitable sample preparation method based on dispersive micro solid-phase extraction
was developed to extract and per-concentrate three anti-cancers, including Imatinib (IMT) …

Discovery and optimization of 2, 3-diaryl-1, 3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity

AM Shawky, FA Almalki, AN Abdalla… - European Journal of …, 2023 - Elsevier
Several studies have indicated the potential therapeutic outcomes of combining selective
COX-2 inhibitors with tubulin-targeting anticancer agents. In the current study, a novel series …

Atorvastatin protects against cyclophosphamide-induced thyroid injury in rats via modulation of JNK/ERK/p38 MAPK signaling pathway

WY Abdelzaher, SA Abdel-Gaber, MA Fawzy… - International …, 2023 - Elsevier
Background Cancer chemotherapy is associated with various tissue toxicities that limit its
use. Cyclophosphamide (CYC) is one of the most commonly used antineoplastic and …