[HTML][HTML] Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

[HTML][HTML] Multi-Mechanistic Approaches to the Treatment of Traumatic Brain Injury: A Review

DG Lynch, RK Narayan, C Li - Journal of Clinical Medicine, 2023 - mdpi.com
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Despite
extensive research efforts, the majority of trialed monotherapies to date have failed to …

Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice

JA Blackwell, JF Silva, EM Louis… - American Journal …, 2022 - journals.physiology.org
Cognitive decline is linked to decreased cerebral blood flow, particularly in women after
menopause. Impaired cerebrovascular function precedes the onset of dementia, possibly …

Delayed CO2 postconditioning promotes neurological recovery after cryogenic traumatic brain injury by downregulating IRF7 expression

Y Li, R Chen, GP Shen, J Yin, Y Li… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims Few treatments are available in the subacute phase of traumatic brain injury (TBI)
except rehabilitation training. We previously reported that transient CO2 inhalation applied …

Propranolol attenuates cognitive, learning, and memory deficits in a murine model of traumatic brain injury

M Zeeshan, M Hamidi, T O'Keeffe, EH Bae… - Journal of Trauma …, 2019 - journals.lww.com
BACKGROUND β-blockers have been shown to improve survival after traumatic brain injury
(TBI); however, the impact of continuous dosage of β-blockers on cognitive function has not …

Remote ischemic conditioning in emergency medicine—clinical frontiers and research opportunities

AFW Ho, J Chong, MEH Ong, DJ Hausenloy - Shock, 2020 - journals.lww.com
Time-critical acute ischemic conditions such as ST-elevation myocardial infarction and acute
ischemic stroke are staples in Emergency Medicine practice. While timely reperfusion …

[HTML][HTML] Neuroadaptive Biochemical Mechanisms of Remote Ischemic Conditioning

K Baranova, N Nalivaeva, E Rybnikova - International Journal of …, 2023 - mdpi.com
This review summarizes the currently known biochemical neuroadaptive mechanisms of
remote ischemic conditioning. In particular, it focuses on the significance of the pro-adaptive …

Preconditioning increases brain resistance against acute brain injury via neuroinflammation modulation

P Gao, S Tang, H Chen, X Zhou, Y Ou, R Shen… - Experimental …, 2021 - Elsevier
Acute brain injury (ABI) is a broad concept mainly comprised of sudden parenchymal brain
injury. Acute brain injury outcomes are dependent not only on the severity of the primary …

Icariin improves functional behavior in a mouse model of traumatic brain injury and promotes synaptic plasticity markers

H Joo, J Bae, JS Lee, Y Bang, BJ Lee, JW Park… - Planta …, 2019 - thieme-connect.com
Epimedii Herba (EH) has been used in traditional Asian medicine to treat hemiplegia
following stroke. Icariin, its major active component, is used as a quality-control marker and …

[HTML][HTML] Effective parameters for gait analysis in experimental models for evaluating peripheral nerve injuries in rats

IM Júnior, P Medeiros, RL de Freita, H Vicente-César… - Neurospine, 2019 - ncbi.nlm.nih.gov
Objective Chronic constriction injury (CCI) of the sciatic nerve is a peripheral nerve injury
widely used to induce mononeuropathy. This study used machine learning methods to …