Development of the human placenta
MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
Tracking placental development in health and disease
Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
[HTML][HTML] Spatial multiomics map of trophoblast development in early pregnancy
A Arutyunyan, K Roberts, K Troulé, FCK Wong… - Nature, 2023 - nature.com
The relationship between the human placenta—the extraembryonic organ made by the
fetus, and the decidua—the mucosal layer of the uterus, is essential to nurture and protect …
fetus, and the decidua—the mucosal layer of the uterus, is essential to nurture and protect …
[HTML][HTML] FIGO (international Federation of Gynecology and obstetrics) initiative on fetal growth: best practice advice for screening, diagnosis, and management of fetal …
Fetal growth restriction (FGR) is defined as the failure of the fetus to meet its growth potential
due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a …
due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
Roles of TGF-β superfamily proteins in extravillous trophoblast invasion
Following embryo implantation, extravillous trophoblasts (EVTs) invade the maternal
decidua to a certain extent during early pregnancy, which is critical for normal placentation …
decidua to a certain extent during early pregnancy, which is critical for normal placentation …
[HTML][HTML] Screening for fetal growth restriction using ultrasound and the sFLT1/PlGF ratio in nulliparous women: a prospective cohort study
F Gaccioli, U Sovio, E Cook, M Hund… - The Lancet Child & …, 2018 - thelancet.com
Background Fetal growth restriction is a major determinant of perinatal morbidity and
mortality. This condition has no gold standard definition, but a widely used proxy is delivery …
mortality. This condition has no gold standard definition, but a widely used proxy is delivery …
[HTML][HTML] The possible role of placental morphometry in the detection of fetal growth restriction
N Salavati, M Smies, W Ganzevoort, AK Charles… - Frontiers in …, 2019 - frontiersin.org
Fetal growth restriction (FGR) is often the result of placental insufficiency and is
characterized by insufficient transplacental transport of nutrients and oxygen. The main …
characterized by insufficient transplacental transport of nutrients and oxygen. The main …
Routine assessment of cerebroplacental ratio at 35–37 weeks' gestation in the prediction of adverse perinatal outcome
R Akolekar, A Ciobanu, E Zingler, A Syngelaki… - American journal of …, 2019 - Elsevier
Background Third-trimester studies in selected high-risk pregnancies have reported that low
cerebroplacental ratio, due to high pulsatility index in the umbilical artery, and or decreased …
cerebroplacental ratio, due to high pulsatility index in the umbilical artery, and or decreased …
Prediction of small for gestational age neonates: screening by maternal factors, fetal biometry, and biomarkers at 35–37 weeks' gestation
A Ciobanu, A Rouvali, A Syngelaki, R Akolekar… - American Journal of …, 2019 - Elsevier
Background Small for gestational age (SGA) neonates are at increased risk for perinatal
mortality and morbidity; however, the risks can be substantially reduced if the condition is …
mortality and morbidity; however, the risks can be substantially reduced if the condition is …