Intravascular imaging assessment of pharmacotherapies targeting atherosclerosis: advantages and limitations in predicting their prognostic implications

V Tufaro, PW Serruys, L Räber… - Cardiovascular …, 2023 - academic.oup.com
Intravascular imaging has been often used over the recent years to examine the efficacy of
emerging therapies targeting plaque evolution. Serial intravascular ultrasound, optical …

High-risk morphological and physiological coronary disease attributes as outcome markers after medical treatment and revascularization

S Yang, BK Koo, D Hwang, J Zhang, M Hoshino… - Cardiovascular …, 2021 - jacc.org
Objectives This study sought to evaluate the prognostic impact of plaque morphology and
coronary physiology on outcomes after medical treatment or percutaneous coronary …

Regression of coronary fatty plaque and risk of cardiac events according to blood pressure status: data From a randomized trial of eicosapentaenoic acid and …

FK Welty, E Hariri, AA Asbeutah, R Daher… - Journal of the …, 2023 - Am Heart Assoc
Background Residual risk of cardiovascular events and plaque progression remains despite
reduction in low‐density lipoprotein cholesterol. Factors contributing to residual risk remain …

Clinical outcome of nonculprit plaque ruptures in patients with acute coronary syndrome in the PROSPECT study

Y Xie, GS Mintz, J Yang, H Doi, A Iñiguez… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The aim of this study was to report the frequency, patient and lesion-related
characteristics, and outcomes of subclinical, nonculprit plaque ruptures in the PROSPECT …

Subclinical carotid atherosclerosis: short-term natural history of lipid-rich necrotic core—a multicenter study with MR imaging

J Sun, N Balu, DS Hippe, Y Xue, L Dong, X Zhao, F Li… - Radiology, 2013 - pubs.rsna.org
Purpose To use magnetic resonance (MR) imaging to examine the short-term (6 months)
natural history of the lipid-rich necrotic core (LRNC) in carotid artery plaques by examining …

The goal of achieving atherosclerotic plaque regression with lipid-lowering therapy: insights from IVUS trials

H Daida, T Dohi, Y Fukushima, H Ohmura… - … of Atherosclerosis and …, 2019 - jstage.jst.go.jp
Atherosclerosis has been classified as the biggest health-care issue around the world1).
Indeed, global health statistics have shown that atherosclerotic cardiovascular disease is the …

Progression of whole-heart Atherosclerosis by coronary CT and major adverse cardiovascular events

AR van Rosendael, FY Lin, IJ van den Hoogen… - Journal of …, 2021 - Elsevier
Background The current study aimed to examine the independent prognostic value of whole-
heart atherosclerosis progression by serial coronary computed tomography angiography …

Familial Hypercholesterolemia: Challenges for a High-Risk Population: JACC Focus Seminar 1/3

D Choi, WA Malick, W Koenig, DJ Rader… - Journal of the American …, 2023 - jacc.org
The availability of statins, ezetimibe, and PCSK9 inhibitors has significantly improved the
prognosis of familial hypercholesterolemia (FH). However, a great number of individuals …

Swine disease models for optimal vascular engineering

M Sturek, M Alloosh, FW Sellke - Annual Review of Biomedical …, 2020 - annualreviews.org
Swine disease models are essential for mimicry of human metabolic and vascular
pathophysiology, thereby enabling high-fidelity translation to human medicine. The …

“In vivo” imaging of atherosclerosis

A Gallino, M Stuber, F Crea, E Falk, R Corti, J Lekakis… - Atherosclerosis, 2012 - Elsevier
Atherosclerosis is a systemic and multifocal disease, which starts early in life, and that
usually takes decades before overt disease eventually appears as a consequence of …