Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

A Wiegman, SS Gidding, GF Watts… - European heart …, 2015 - academic.oup.com
Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary
heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and …

Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation

GF Watts, S Gidding, AS Wierzbicki, PP Toth… - International journal of …, 2014 - Elsevier
Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth
that markedly elevates plasma low-density lipoprotein (LDL) cholesterol and causes …

Predictors of statin adherence, switching, and discontinuation in the USAGE survey: understanding the use of statins in America and gaps in patient education

MY Wei, MK Ito, JD Cohen, EA Brinton… - Journal of clinical …, 2013 - Elsevier
Background Although statins have been shown to reduce cardiovascular disease mortality,
less than half of US adults achieve their low-density lipoprotein cholesterol goal. In many …

[HTML][HTML] Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain–a systematic review and meta-analysis

MC Gerards, RJ Terlou, H Yu, CHW Koks, VEA Gerdes - Atherosclerosis, 2015 - Elsevier
Objective To verify the safety and effectiveness of traditional Chinese red yeast rice-extract
(RYR) for reduction of LDL cholesterol. Methods Systematic literature review and meta …

Familial hypercholesterolaemia: a model of care for Australasia

GF Watts, DR Sullivan, N Poplawski… - Atherosclerosis …, 2011 - Elsevier
Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth
that causes marked elevation in plasma cholesterol and premature coronary heart disease …

Inclisiran for the treatment of cardiovascular disease: a short review on the emerging data and therapeutic potential

CE Kosmas, A Muñoz Estrella, A Skavdis… - … and Clinical Risk …, 2020 - Taylor & Francis
Proprotein convertase subtilisin kexin 9 (PCSK-9)-targeting therapy has arisen as a new line
for the treatment of hyperlipidemia. Inclisiran is a double-stranded small RNA molecule that …

Integrated guidance on the care of familial hypercholesterolemia from the International FH Foundation

GF Watts, S Gidding, AS Wierzbicki, PP Toth… - Journal of Clinical …, 2014 - Elsevier
Familial hypercholesterolemia (FH) is a dominantly inherited disorder present from birth that
markedly elevates plasma low-density lipoprotein cholesterol and causes premature …

Systematic review: non-adherence and non-persistence in intravitreal treatment

C Ehlken, F Ziemssen, N Eter, I Lanzl… - Graefe's Archive for …, 2020 - Springer
Purpose Intravitreal injection of VEGF inhibitors has become the standard of care for
different macular diseases within the last years resulting in improved visual outcomes …

Assessment of sex disparities in nonacceptance of statin therapy and low-density lipoprotein cholesterol levels among patients at high cardiovascular risk

CJ Brown, LS Chang, N Hosomura… - JAMA Network …, 2023 - jamanetwork.com
Importance Many patients at high cardiovascular risk—women more commonly than men—
are not receiving statins. Anecdotally, it is common for patients to not accept statin therapy …

Prevalence of the American College of Cardiology/American Heart Association statin eligibility groups, statin use, and low-density lipoprotein cholesterol control in US …

ND Wong, D Young, Y Zhao, H Nguyen… - Journal of clinical …, 2016 - Elsevier
Background The 2013 American College of Cardiology/American Heart Association
Cholesterol Management Guideline identifies 4 statin-eligible groups:(1) known …