Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …

Messenger RNA (mRNA) vaccine development for preventive and therapeutic applications
has evolved rapidly over the last decade. The mRVNA vaccine has proven therapeutic …

Messenger RNA (mRNA) is a new class of therapeutic compounds. The current advances in
mRNA technology require the development of efficient analytical methods. In this work, we …

Chagas disease (CD)(American trypanosomiasis caused by Trypanosoma cruzi) is a
parasitic disease endemic in 21 countries in South America, with increasing global spread …

Gastrointestinal tumors remain a significant healthcare burden worldwide, necessitating the
development of innovative therapeutic strategies. mRNA vaccines have emerged as a …

Despite the availability of live-attenuated oral vaccines, rotavirus remains a major cause of
severe childhood diarrhea worldwide. Due to the growing demand for parenteral rotavirus …

RNA is prone to both chemical degradation and/or physical instability. Some of the factors
affecting stability of RNA in solution are its length, 3′ poly A tail and 5′ cap integrity …

The two primary narratives that have emerged to explain low COVID-19 vaccine uptake in
low-and middle-income countries are constrained accessibility and vaccine hesitancy …

Nano-sized biomaterials are innovative drug carriers with nanometric dimensions. Designed
with biocompatibility in mind, they enable precise drug delivery while minimizing side …

Crimean–Congo hemorrhagic fever virus (CCHFV), a member of the Nairoviridae family and
Bunyavirales order, is transmitted to humans via tick bites or contact with the blood of …