Biology of natural killer cells
G Trinchieri - Advances in immunology, 1989 - Elsevier
Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …
Human natural killer cells: origin, clonality, specificity, and receptors
L Moretta, E Ciccone, MC Mingari, R Biassoni… - Advances in …, 1993 - Elsevier
Publisher Summary This chapter focuses on human natural killer (NK) cells. NK cells are
considered as effector cells that lyse tumor cells or virally infected cells via nonspecific …
considered as effector cells that lyse tumor cells or virally infected cells via nonspecific …
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells
Two major receptors involved in human natural cytotoxicity, NKp46 and NKp44, have
recently been identified. However, experimental evidence suggested the existence of …
recently been identified. However, experimental evidence suggested the existence of …
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity
NKp46 has been shown to represent a novel, natural killer (NK) cell–specific surface
molecule, involved in human NK cell activation. In this study, we further analyzed the role of …
molecule, involved in human NK cell activation. In this study, we further analyzed the role of …
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily
Surface receptors involved in natural killer (NK) cell triggering during the process of tumor
cell lysis have recently been identified. Of these receptors, NKp44 is selectively expressed …
cell lysis have recently been identified. Of these receptors, NKp44 is selectively expressed …
Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells
LL Lanier, G Yu, JH Phillips - Nature, 1989 - nature.com
NATURAL killer (NK) cells are a subset of lymphocytes that mediate major histocompatibility
complex (MHC)-nonrestricted cytotoxicity against tumours and virus-infected cells and …
complex (MHC)-nonrestricted cytotoxicity against tumours and virus-infected cells and …
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between …
In previous studies we identified a surface molecule (termed GL183) capable of mediating
cell activation and selectively expressed by a subset of human CD3-CD16+ natural killer …
cell activation and selectively expressed by a subset of human CD3-CD16+ natural killer …
Gntb-A, a Novel Sh2d1a-Associated Surface Molecule Contributing to the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected B Cells in X-Linked …
In humans, natural killer (NK) cell function is regulated by a series of receptors and
coreceptors with either triggering or inhibitory activity. Here we describe a novel 60-kD …
coreceptors with either triggering or inhibitory activity. Here we describe a novel 60-kD …
A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.
The GL183 mAb was obtained by immunizing BALB/c mice with the E57 clone (CD7+ CD2+
CD3-CD16+ CD56+) derived from human peripheral blood NK cells. In human peripheral …
CD3-CD16+ CD56+) derived from human peripheral blood NK cells. In human peripheral …
Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon, delta proteins.
Natural killer (NK) cells have been defined as CD3 epsilon-, CD16+ and/or CD56+
lymphocytes that mediate major histocompatibility complex (MHC)-unrestricted cytotoxicity …
lymphocytes that mediate major histocompatibility complex (MHC)-unrestricted cytotoxicity …