Inhaled medicines: past, present, and future
The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …
[HTML][HTML] Optimizing drug delivery in COPD: the role of inhaler devices
P Rogliani, L Calzetta, A Coppola, F Cavalli, J Ora… - Respiratory …, 2017 - Elsevier
Background Inhaled medication is the cornerstone of the pharmacological treatment for
patients with asthma and chronic obstructive pulmonary disease (COPD). Several inhaler …
patients with asthma and chronic obstructive pulmonary disease (COPD). Several inhaler …
Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
Emerging inhalation aerosol devices and strategies: where are we headed?
Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …
to innovations in designing suitable delivery systems. These emerging design technologies …
Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: an emerging need for novel drug delivery systems
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
Advances in metered dose inhaler technology: formulation development
PB Myrdal, P Sheth, SW Stein - Aaps Pharmscitech, 2014 - Springer
Pressurized metered dose inhalers (MDIs) are a long-standing method to treat diseases of
the lung, such as asthma and chronic obstructive pulmonary disease. MDIs rely on the …
the lung, such as asthma and chronic obstructive pulmonary disease. MDIs rely on the …
[HTML][HTML] Efficacy and safety of glycopyrrolate/formoterol metered dose inhaler formulated using co-suspension delivery technology in patients with COPD
Background Long-acting muscarinic antagonist (LAMA)/long-acting β 2-agonist (LABA)
combinations are a treatment option for patients with COPD who continue to have symptoms …
combinations are a treatment option for patients with COPD who continue to have symptoms …
Lipid-based carriers for pulmonary products: preclinical development and case studies in humans
D Cipolla, B Shekunov, J Blanchard… - Advanced drug delivery …, 2014 - Elsevier
A number of lipid-based technologies have been applied to pharmaceuticals to modify their
drug release characteristics, and additionally, to improve the drug loading for poorly soluble …
drug release characteristics, and additionally, to improve the drug loading for poorly soluble …
The PulmoSphere™ platform for pulmonary drug delivery
J Weers, T Tarara - Therapeutic delivery, 2014 - Future Science
Spray–dried PulmoSphere™ formulations comprise phospholipid-based small, porous
particles. Drug (s) may be incorporated in or with PulmoSphere formulations in three …
particles. Drug (s) may be incorporated in or with PulmoSphere formulations in three …
Delivery technologies for orally inhaled products: an update
Orally inhaled products have well-known benefits. They allow for effective local
administration of many drugs for the treatment of pulmonary disease, and they allow for …
administration of many drugs for the treatment of pulmonary disease, and they allow for …