Sepsis presents as a severe infectious disease frequently documented in clinical settings.
Characterized by its systemic inflammatory response syndrome, sepsis has the potential to …

Lindera aggregata (Sims) Kosterm.(L. aggregata), which belongs to the genus Lindera in the
family Lauraceae, is widely distributed in Asia and the temperate, tropical regions of North …

Objective NLRP3 inflammasome-mediated pyroptosis of macrophage acts essential roles in
the progression of sepsis-induced acute lung injury (ALI). Tangeretin (TAN), enriched in …

Sepsis is a manifestation of the immune and inflammatory response to infection, which may
lead to multi‑organ failure. Health care advances have improved outcomes in critical illness …

Norisoboldine (NOR), the major isoquinoline alkaloid constituent of a Chinese traditional
medicine Radix Linderae, has been demonstrated to inhibit osteoclast differentiation and …

Abstract Pyruvate kinase M2 (PKM2) is a key rate-limiting enzyme in glycolysis. It is well
known that PKM2 plays a vital role in the proliferation of tumor cells. However, PKM2 can …

Background: Sepsis-induced acute lung injury (ALI) is a syndrome associated with
inflammation. Cornus iridoid glycoside (CIG), a bioactive component isolated from Corni …

Sepsis is characterized by organ dysfunction resulting from a dysregulated inflammatory
response triggered by infection, involving multifactorial and intricate molecular mechanisms …

The apoptosis and inflammation of pulmonary epithelial cells are important pathogenic
factors of sepsis-induced acute lung injury (ALI). Upregulation of circPalm2 (circ_0001212) …

Colorectal cancer (CRC) is a malignant tumor of the gastrointestinal tract that significantly
impacts the health of patients and lacks promising methods of diagnosis. Tumor-associated …