Heat shock proteins (HSP) were first identified in cells after exposure to elevated
temperature. Subsequently HSP have been identified as a critical component of a very …

Gastrointestinal distress, such as diarrhoea, cramping, vomiting, nausea and gastric pain
are common among athletes during training and competition. The mechanisms that cause …

Taxol can mimic bacterial lipopolysaccharide (LPS) by activating mouse macrophages in a
cell cycle‐independent, LPS antagonist‐inhibitable manner. Macrophages from C3H/HeJ …

Ageing is associated with skeletal muscle atrophy, a deficit in force generation, an increased
susceptibility to contraction-induced injury, and a permanent force deficit following severe …

The eukaryotic cell depends on multitiered homeostatic systems ensuring maintenance of
proteostasis, organellar integrity, function and turnover, and overall cellular viability. At the …

The 70-kDa heat shock protein (Hsp70) is involved in protecting the brain from a variety of
insults including stroke. Although the mechanism has been largely considered to be …

Extracellular heat-shock proteins (eHsp) such as those belonging to the 70-kDa family of
Hsp (eg, Hsp72) have been hypothesized to act as a “danger signal” to immune cells …

Sepsis is a highly lethal clinical syndrome characterized by a systemic inflammatory
response to infection. Fever, a non-specific acute-phase response, has been associated …

Heat shock protein (Hsp) 70 has been reported to protect various cells and tissues from
ischemic damage. However, the molecular mechanisms of the protection are incompletely …

Since the inception of the field of psychoneuroimmunolology research, there has been an
appreciation that the physiological response to stressors includes modulation of immune …