Epigenetic regulation of fibroblasts and crosstalk between Cardiomyocytes and Non-myocyte cells in Cardiac Fibrosis

L Chu, D Xie, D Xu - Biomolecules, 2023 - mdpi.com
Epigenetic mechanisms and cell crosstalk have been shown to play important roles in the
initiation and progression of cardiac fibrosis. This review article aims to provide a thorough …

Mechanotransductive receptor Piezo1 as a promising target in the treatment of fibrosis diseases

Y Xu, Y Huang, X Cheng, B Hu, D Jiang… - Frontiers in Molecular …, 2023 - frontiersin.org
Fibrosis could happen in every organ, leading to organic malfunction and even organ
failure, which poses a serious threat to global health. Early treatment of fibrosis has been …

Mechanosensing by Piezo1 and its implications in the kidney

X Yuan, X Zhao, W Wang, C Li - Acta Physiologica, 2024 - Wiley Online Library
Piezo1 is an essential mechanosensitive transduction ion channel in mammals. Its unique
structure makes it capable of converting mechanical cues into electrical and biological …

Mechanism of sodium butyrate, a metabolite of gut microbiota, regulating cardiac fibroblast transdifferentiation via the NLRP3/Caspase-1 pyroptosis pathway

T Dong, D Huang, Z Jin - Journal of Cardiothoracic Surgery, 2024 - Springer
Abstract Background Cardiac fibroblasts (CFs) are activated after initial injury, and then
differentiate into myofibroblasts (MFs), which play a pivotal role as the primary mediator cells …

βIV-Spectrin in Cardiac Fibroblasts: Implications for Fibrosis and Therapeutic Targeting in Cardiac Diseases. Comment on Nassal et al. Spectrin-Based Regulation of …

W Xiang, N Zhou, L Li, F Chen, L Li, Y Wang - Cells, 2023 - mdpi.com
Cells | Free Full-Text | βIV-Spectrin in Cardiac Fibroblasts: Implications for Fibrosis and
Therapeutic Targeting in Cardiac Diseases. Comment on Nassal et al. Spectrin-Based …

Promising Therapeutic Treatments for Cardiac Fibrosis: Herbal Plants and Their Extracts

X Yu - Cardiology and Therapy, 2023 - Springer
Cardiac fibrosis is closely associated with multiple heart diseases, which are a prominent
health issue in the global world. Neurohormones and cytokines play indispensable roles in …