[HTML][HTML] Lactoferrin: A glycoprotein that plays an active role in human health

X Cao, Y Ren, Q Lu, K Wang, Y Wu, YH Wang… - Frontiers in …, 2023 - frontiersin.org
Lactoferrin (Lf), existing widely in human and mammalian milk, is a multifunctional
glycoprotein with many functions, such as immune regulation, anti-inflammation …

[HTML][HTML] Nutraceutical and health-promoting potential of lactoferrin, an iron-binding protein in human and animal: current knowledge

MF Ashraf, D Zubair, MN Bashir, M Alagawany… - … Trace Element Research, 2024 - Springer
Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in
bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile …

[HTML][HTML] Studying Lactoferrin N-Glycosylation

S Karav, JB German, C Rouquié, A Le Parc… - International journal of …, 2017 - mdpi.com
Lactoferrin is a multifunctional glycoprotein found in the milk of most mammals. In addition to
its well-known role of binding iron, lactoferrin carries many important biological functions …

[HTML][HTML] Lactoferrin as a Human Genome “Guardian”—An Overall Point of View

I Bukowska-Ośko, D Sulejczak, K Kaczyńska… - International Journal of …, 2022 - mdpi.com
Structural abnormalities causing DNA modifications of the ethene and propanoadducts can
lead to mutations and permanent damage to human genetic material. Such changes may …

[HTML][HTML] Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle

B Yang, J Wang, B Tang, Y Liu, C Guo, P Yang, T Yu… - PloS one, 2011 - journals.plos.org
Background There is great potential for using transgenic technology to improve the quality of
cow milk and to produce biopharmaceuticals within the mammary gland. Lysozyme, a …

[HTML][HTML] Use of transgenic animals in biotechnology: prospects and problems

OG Maksimenko, AV Deykin… - Acta Naturae …, 2013 - cyberleninka.ru
During the past two decades, there have been numerous attempts at using animals in order
to produce recombinant human proteins and monoclonal antibodies. However, it is only …

Precision editing of large animal genomes

DF Carlson, MW Walton, SC Fahrenkrug, PB Hackett - Advances in …, 2012 - Elsevier
Transgenic animals are an important source of protein and nutrition for most humans and
will play key roles in satisfying the increasing demand for food in an ever-increasing world …

[HTML][HTML] Gene targeting by TALEN-induced homologous recombination in goats directs production of β-lactoglobulin-free, high-human lactoferrin milk

C Cui, Y Song, J Liu, H Ge, Q Li, H Huang, L Hu… - Scientific reports, 2015 - nature.com
Abstract β-Lactoglobulin (BLG) is a major goat's milk allergen that is absent in human milk.
Engineered endonucleases, including transcription activator-like effector nucleases …

Improving livestock for agriculture–technological progress from random transgenesis to precision genome editing heralds a new era

G Laible, J Wei, S Wagner - Biotechnology journal, 2015 - Wiley Online Library
Humans have a long history in shaping the genetic makeup of livestock to optimize
production and meet growing human demands for food and other animal products. Until …

[HTML][HTML] Production of hypoallergenic milk from DNA-free beta-lactoglobulin (BLG) gene knockout cow using zinc-finger nucleases mRNA

Z Sun, M Wang, S Han, S Ma, Z Zou, F Ding, X Li… - Scientific Reports, 2018 - nature.com
The whey protein β-lactoglobulin (BLG) is a major milk allergen which is absent in human
milk. Here, we for the first time generated DNA-free BLG bi-allelic knockout cow by zinc …