Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms

WL Lee, JY Huang, LF Shyur - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Accumulation of oxidized nucleic acids causes genomic instability leading to senescence,
apoptosis, and tumorigenesis. Phytoagents are known to reduce the risk of cancer …

Chronic obstructive pulmonary disease and lung cancer: underlying pathophysiology and new therapeutic modalities

MS Eapen, PM Hansbro, AK Larsson‑Callerfelt… - Drugs, 2018 - Springer
Chronic obstructive pulmonary disease (COPD) and lung cancer are major lung diseases
affecting millions worldwide. Both diseases have links to cigarette smoking and exert a …

Nutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidence

A Samoylenko, JA Hossain, D Mennerich… - Antioxidants & redox …, 2013 - liebertpub.com
Reactive oxygen species (ROS) exert various biological effects and contribute to signaling
events during physiological and pathological processes. Enhanced levels of ROS are highly …

Behavioural changes, sharing behaviour and psychological responses after receiving direct-to-consumer genetic test results: a systematic review and meta-analysis

KFJ Stewart, A Wesselius, MAC Schreurs… - Journal of community …, 2018 - Springer
It has been hypothesised that direct-to-consumer genetic tests (DTC-GTs) could stimulate
health behaviour change. However, genetic testing may also lead to anxiety and distress or …

Serum antioxidant nutrients, vitamin A, and mortality in US adults

A Goyal, MB Terry, AB Siegel - Cancer epidemiology, biomarkers & …, 2013 - AACR
Background: Observational studies have suggested that antioxidant nutrients may reduce
cancer and overall mortality risks. However, most randomized trials have failed to show …

Role of vitamin E in the treatment of non-alcoholic steatohepatitis

Y Sumida, M Yoneda, Y Seko, H Takahashi… - Free Radical Biology …, 2021 - Elsevier
Abstract Non-alcoholic steatohepatitis (NASH), a severe form of non-alcoholic fatty liver
disease (NAFLD), can progress to cirrhosis, hepatocellular carcinoma (HCC), and hepatic …

Cytochrome c oxidase inhibition and cold plasma-derived oxidants synergize in melanoma cell death induction

RK Gandhirajan, K Rödder, Y Bodnar… - Scientific reports, 2018 - nature.com
Despite striking advances in the treatment of metastasized melanoma, the disease is often
still fatal. Attention is therefore paid towards combinational regimens. Oxidants …

Combined effect of aerobic interval training and selenium nanoparticles on expression of IL-15 and IL-10/TNF-α ratio in skeletal muscle of 4T1 breast cancer mice with …

MM Shamsi, S Chekachak, S Soudi, LS Quinn… - Cytokine, 2017 - Elsevier
Cancer cachexia is characterized by inflammation, loss of skeletal muscle and adipose
tissue mass, and functional impairment. Oxidative stress and inflammation are believed to …

Knowledge about dietary supplements and trust in advertising them: Development and validation of the questionnaires and preliminary results of the association …

MS Karbownik, E Paul, M Nowicka, Z Nowicka… - PLoS …, 2019 - journals.plos.org
Background Despite offering little overall benefit and emerging concerns about their safety,
dietary supplements have become increasingly popular. Trust in advertising them may …

Inflammation, DAMPs, tumor development, and progression: a vicious circle orchestrated by redox signaling

P Castellani, E Balza, A Rubartelli - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Increasing evidence indicates that cancer development and progression are
promoted by the joint action of redox distress and inflammation, supporting the potential …