From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I

M Naghavi, P Libby, E Falk, SW Casscells, S Litovsky… - Circulation, 2003 - Am Heart Assoc
Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …

Vascular repair by endothelial progenitor cells

A Zampetaki, JP Kirton, Q Xu - Cardiovascular research, 2008 - academic.oup.com
Accumulating evidence indicates the impact of endothelial progenitor cells (EPCs) in
vascular repair. In patients, the number of EPCs is negatively correlated with the severity of …

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

A Luttun, M Tjwa, L Moons, Y Wu… - Nature medicine, 2002 - nature.com
The therapeutic potential of placental growth factor (PlGF) and its receptor Flt1 in
angiogenesis is poorly understood. Here, we report that PlGF stimulated angiogenesis and …

Tumors resurrect an embryonic vascular program to escape immunity

EJM Huijbers, KA Khan, RS Kerbel, AW Griffioen - Science immunology, 2022 - science.org
Tumors can escape immunity through multiple mechanisms, one of which is by enforcing a
state of unresponsiveness of the tumor vasculature to inflammatory cytokines. This results in …

Angiogenesis: where do we stand now?

M Simons - Circulation, 2005 - Am Heart Assoc
The role of preexisting collateral channels in the heart is far less well established. Early
studies failed to show the existence of coronary-to-coronary artery connection in normal …

Advanced glycation end products: a molecular target for vascular complications in diabetes

S Yamagishi, N Nakamura, M Suematsu, K Kaseda… - Molecular …, 2015 - Springer
A nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids and
nucleic acids contributes to the aging of macromolecules and subsequently alters their …

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor–deficient mice

GK Sukhova, Y Zhang, JH Pan, Y Wada… - The Journal of …, 2003 - Am Soc Clin Investig
Human atherosclerotic lesions overexpress the lysosomal cysteine protease cathepsin S
(Cat S), one of the most potent mammalian elastases known. In contrast, atheromata have …

Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization

SB Feinstein - Journal of the American College of Cardiology, 2006 - jacc.org
Contrast Ultrasound Imaging of the Carotid Artery Vasa Vasorum and Atherosclerotic Plaque
Neovascularization Steven B. Feinstein Cardiovascular disease is associated with the aging …

Intracranial vasa vasorum: insights and implications for imaging

A Portanova, N Hakakian, DJ Mikulis, R Virmani… - Radiology, 2013 - pubs.rsna.org
This review offers insight into the possible role of vasa vasorum in the development of
intracranial vascular disease. Unique structural features of intracranial vessels and …

A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use

FTH Wu, MO Stefanini, FM Gabhann… - Journal of cellular …, 2010 - Wiley Online Library
Introduction‐Angiogenesis in physiology and pathology‐Angiogenesis in current medicine‐
VEGF ligand and receptor system: where does sVEGFR1 fit?‐Ligands: the human VEGF …