From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …
heart disease accounts for the majority of this toll. Despite major advances in treatment of …
Vascular repair by endothelial progenitor cells
A Zampetaki, JP Kirton, Q Xu - Cardiovascular research, 2008 - academic.oup.com
Accumulating evidence indicates the impact of endothelial progenitor cells (EPCs) in
vascular repair. In patients, the number of EPCs is negatively correlated with the severity of …
vascular repair. In patients, the number of EPCs is negatively correlated with the severity of …
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
A Luttun, M Tjwa, L Moons, Y Wu… - Nature medicine, 2002 - nature.com
The therapeutic potential of placental growth factor (PlGF) and its receptor Flt1 in
angiogenesis is poorly understood. Here, we report that PlGF stimulated angiogenesis and …
angiogenesis is poorly understood. Here, we report that PlGF stimulated angiogenesis and …
Tumors resurrect an embryonic vascular program to escape immunity
Tumors can escape immunity through multiple mechanisms, one of which is by enforcing a
state of unresponsiveness of the tumor vasculature to inflammatory cytokines. This results in …
state of unresponsiveness of the tumor vasculature to inflammatory cytokines. This results in …
Angiogenesis: where do we stand now?
M Simons - Circulation, 2005 - Am Heart Assoc
The role of preexisting collateral channels in the heart is far less well established. Early
studies failed to show the existence of coronary-to-coronary artery connection in normal …
studies failed to show the existence of coronary-to-coronary artery connection in normal …
Advanced glycation end products: a molecular target for vascular complications in diabetes
S Yamagishi, N Nakamura, M Suematsu, K Kaseda… - Molecular …, 2015 - Springer
A nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids and
nucleic acids contributes to the aging of macromolecules and subsequently alters their …
nucleic acids contributes to the aging of macromolecules and subsequently alters their …
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor–deficient mice
GK Sukhova, Y Zhang, JH Pan, Y Wada… - The Journal of …, 2003 - Am Soc Clin Investig
Human atherosclerotic lesions overexpress the lysosomal cysteine protease cathepsin S
(Cat S), one of the most potent mammalian elastases known. In contrast, atheromata have …
(Cat S), one of the most potent mammalian elastases known. In contrast, atheromata have …
Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization
SB Feinstein - Journal of the American College of Cardiology, 2006 - jacc.org
Contrast Ultrasound Imaging of the Carotid Artery Vasa Vasorum and Atherosclerotic Plaque
Neovascularization Steven B. Feinstein Cardiovascular disease is associated with the aging …
Neovascularization Steven B. Feinstein Cardiovascular disease is associated with the aging …
Intracranial vasa vasorum: insights and implications for imaging
A Portanova, N Hakakian, DJ Mikulis, R Virmani… - Radiology, 2013 - pubs.rsna.org
This review offers insight into the possible role of vasa vasorum in the development of
intracranial vascular disease. Unique structural features of intracranial vessels and …
intracranial vascular disease. Unique structural features of intracranial vessels and …
A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use
FTH Wu, MO Stefanini, FM Gabhann… - Journal of cellular …, 2010 - Wiley Online Library
Introduction‐Angiogenesis in physiology and pathology‐Angiogenesis in current medicine‐
VEGF ligand and receptor system: where does sVEGFR1 fit?‐Ligands: the human VEGF …
VEGF ligand and receptor system: where does sVEGFR1 fit?‐Ligands: the human VEGF …