Dopamine targeting drugs for the treatment of schizophrenia: past, present and future

P Li, GL Snyder, KE Vanover - Current topics in medicinal …, 2016 - ingentaconnect.com
Schizophrenia is a chronic and debilitating neuropsychiatric disorder affecting
approximately 1% of the world's population. This disease is associated with considerable …

[HTML][HTML] Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity

D Val-Laillet, E Aarts, B Weber, M Ferrari… - NeuroImage: Clinical, 2015 - Elsevier
Functional, molecular and genetic neuroimaging has highlighted the existence of brain
anomalies and neural vulnerability factors related to obesity and eating disorders such as …

The role of reward circuitry and food addiction in the obesity epidemic: An update

SJ Leigh, MJ Morris - Biological psychology, 2018 - Elsevier
The increasing worldwide prevalence of obesity is partially related to the ready availability of
highly palatable foods which increases the incidence of hedonic, non-homeostatic feeding …

Uncontrolled eating: a unifying heritable trait linked with obesity, overeating, personality and the brain

U Vainik, I García‐García… - European Journal of …, 2019 - Wiley Online Library
Many eating‐related psychological constructs have been proposed to explain obesity and
overeating. However, these constructs, including food addiction, disinhibition, hedonic …

Dopamine and glucose, obesity, and reward deficiency syndrome

K Blum, PK Thanos, MS Gold - Frontiers in psychology, 2014 - frontiersin.org
Obesity as a result of overeating as well as a number of well described eating disorders has
been accurately considered to be a world-wide epidemic. Recently a number of theories …

[HTML][HTML] Obesity and the neurocognitive basis of food reward and the control of intake

H Ziauddeen, M Alonso-Alonso, JO Hill, M Kelley… - Advances in …, 2015 - Elsevier
With the rising prevalence of obesity, hedonic eating has become an important theme in
obesity research. Hedonic eating is thought to be that driven by the reward of food …

A meta-analysis of the relationship between brain dopamine receptors and obesity: a matter of changes in behavior rather than food addiction?

D Benton, HA Young - International journal of obesity, 2016 - nature.com
Addiction to a wide range of substances of abuse has been suggested to reflect a 'Reward
Deficiency Syndrome'. That is, drugs are said to stimulate the reward mechanisms so …

Striatal dopamine D2-like receptor correlation patterns with human obesity and opportunistic eating behavior

J Guo, WK Simmons, P Herscovitch, A Martin… - Molecular …, 2014 - nature.com
The obesity epidemic is believed to be driven by a food environment that promotes
consumption of inexpensive, convenient, high-calorie, palatable foods. Individual …

Bariatric surgery‐induced weight loss causes remission of food addiction in extreme obesity

MY Pepino, RI Stein, JC Eagon, S Klein - Obesity, 2014 - Wiley Online Library
Objective To test the hypotheses that bariatric surgery‐induced weight loss: induces
remission of food addiction (FA), and normalizes other eating behaviors associated with FA …

Neuroinflammation and white matter alterations in obesity assessed by diffusion basis spectrum imaging

A Samara, T Murphy, J Strain, J Rutlin, P Sun… - Frontiers in Human …, 2020 - frontiersin.org
Human obesity is associated with low-grade chronic systemic inflammation, alterations in
brain structure and function, and cognitive impairment. Rodent models of obesity show that …