Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety
of community and hospital infections. Infections caused by carbapenem-resistant K …

The making of hypervirulent Klebsiella pneumoniae

P Dai, D Hu - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐
resistance and their convergence among K. pneumoniae are extensively discussed in this …

Characterization difference of typical KL1, KL2 and ST11-KL64 hypervirulent and carbapenem-resistant Klebsiella pneumoniae

Y Zhou, C Wu, B Wang, YL Xu, H Zhao, Y Guo… - Drug Resistance …, 2023 - Elsevier
Almost all the formation of hypervirulent and carbapenem-resistant Klebsiella pneumoniae
follow two major patterns: KL1/KL2 hvKP strains acquire carbapenem-resistance plasmids …

[HTML][HTML] “Superbugs” with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China

D Pu, J Zhao, K Chang, X Zhuo, B Cao - Science Bulletin, 2023 - Elsevier
Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …

Outer Membrane Vesicles Transmitting blaNDM-1 Mediate the Emergence of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae

B Tang, A Yang, P Liu, Z Wang, Z Jian… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Dissemination of hypervirulent and carbapenem-resistant Klebsiella pneumoniae (CRKP)
has been reported worldwide, posing a serious threat to antimicrobial therapy and public …

Mobilizable plasmids drive the spread of antimicrobial resistance genes and virulence genes in Klebsiella pneumoniae

J Zhang, Y Xu, M Wang, X Li, Z Liu, D Kuang, Z Deng… - Genome Medicine, 2023 - Springer
Background Klebsiella pneumoniae is a notorious clinical pathogen and frequently carries
various plasmids, which are the main carriers of antimicrobial resistance and virulence …

[HTML][HTML] Regulation of biofilm formation in Klebsiella pneumoniae

Y Li, M Ni - Frontiers in Microbiology, 2023 - frontiersin.org
Klebsiella pneumoniae is an important Gram-negative opportunistic pathogen that is
responsible for a variety of nosocomial and community-acquired infections. Klebsiella …

Epidemiological characteristics of SHV, cmlv, and FosA6-producing carbapenem-resistant Klebsiella pneumoniae based on whole genome sequences in Jiangsu …

J Zhu, Y Ju, X Zhou, T Chen, X Zhuge… - Frontiers in Microbiology, 2023 - frontiersin.org
Carbapenem-resistant Klebsiella pneumoniae (CRKP), particularly those with high
virulence, cause invasive disease in clinical settings. An epidemiological investigation was …

[HTML][HTML] Detection of carbapenem-resistant hypervirulent Klebsiella pneumoniae ST11-K64 co-producing NDM-1 and KPC-2 in a tertiary hospital in Wuhan

Y Huang, J Li, Q Wang, K Tang, X Cai, C Li - Journal of Hospital Infection, 2023 - Elsevier
Summary Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-
hvKP) poses serious challenges to public health. Only a few sporadic reports of strains co …

Genomic insights unveil the plasmid transfer mechanism and epidemiology of hypervirulent Klebsiella pneumoniae in Vietnam

Q Nguyen, YTP Nguyen, TT Ha, DTN Tran… - Nature …, 2024 - nature.com
Hypervirulent Klebsiella pneumoniae (hvKp) is a significant cause of severe invasive
infections in Vietnam, yet data on its epidemiology, population structure and dynamics are …