Inhibition of intestinal α‐glucosidase (αGS), a crucial enzyme in carbohydrate digestion, is
an effective therapeutic approach for diabetes mellitus treatment. The C‐glycosylflavonoids …

A drug Mechanism of Action (MoA) is a complex biological phenomenon that describes how
a bioactive compound produces a pharmacological effect. The complete knowledge of MoA …

To address increasing demands of computational resources, scientific applications started to
support different type of hardware accelerators, eg, GPUs, TPUs, ASICs. However, due to …

AKT (also known as PKB) is a serine/threonine kinase that plays a pivotal regulatory role in
the PI3K/AKT/mTOR signaling pathway. Dysregulation of AKT activity, especially its …

L'intelligence artificielle (IA) et l'apprentissage automatique produisent des modèles
prédictifs qui aident à la prise de décisions dans le processus de découverte de nouveaux …

Pharmaceutical development constitutes a highly complex process with several steps that
need to be completed for bringing a new safe and effective drug into the market. This …

Traditional drug discovery often involves laborious and time-consuming processes.
However, emerging artificial intelligence (AI)-based models offer new ways to expedite the …

Dengue virus (DENV) non-structural protein 1 (NS1) is a versatile quasi-protein essential for
the multiplication of the virus. This study applied high-throughput virtual screening (HTVS) …

Aim: This study aims to develop a cloud-based digital healthcare system for precision
medical hospital information systems (P-HIS). Methods: In 2020, international …

Historically, drug discovery was dominated by relentless scientific experiments and
repetitive laboratory procedures. However, with the introduction of computational …