Antioxidant defence systems and oxidative stress in poultry biology: An update
PF Surai, II Kochish, VI Fisinin, MT Kidd - Antioxidants, 2019 - mdpi.com
Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …
information clearly indicates that excess ROS/RNS production and oxidative stress are …
Molecular mechanisms of action of genistein in cancer: Recent advances
HS Tuli, MJ Tuorkey, F Thakral, K Sak… - Frontiers in …, 2019 - frontiersin.org
Background: Genistein is one among the several other known isoflavones that is found in
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …
Natural and synthetic compounds in Ovarian Cancer: A focus on NRF2/KEAP1 pathway
G Tossetta, D Marzioni - Pharmacological Research, 2022 - Elsevier
Among gynecologic malignancies, ovarian cancer is one of the most dangerous, with a high
fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
Genistein: a potent anti-breast cancer agent
Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …
Plants as a source of anticancer agents: From bench to bedside
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
Modulation of Nrf2 and NF-κB signaling pathways by naturally occurring compounds in relation to cancer prevention and therapy. Are combinations better than single …
V Krajka-Kuźniak, W Baer-Dubowska - International Journal of Molecular …, 2021 - mdpi.com
Nrf2 (nuclear factor erythroid 2-related factor 2) and NF-κB (nuclear factor–kappa B)
signaling pathways play a central role in suppressing or inducing inflammation and …
signaling pathways play a central role in suppressing or inducing inflammation and …
Redox activity of flavonoids: Impact on human health, therapeutics, and chemical safety
C Sarkar, P Chaudhary, S Jamaddar… - Chemical Research …, 2022 - ACS Publications
The cost-effectiveness of presently used therapies is a problem in overall redox-based
management, which is posing a significant financial burden on communities across the …
management, which is posing a significant financial burden on communities across the …
Cellular and molecular mechanisms of genistein in prevention and treatment of diseases: An overview
F Nazari‐Khanamiri… - Journal of Food …, 2021 - Wiley Online Library
Genistein is the simplest secondary metabolite in soybeans and belongs to a group of
compounds called isoflavones. It is a phytoestrogen and it makes up more than 60% of soy …
compounds called isoflavones. It is a phytoestrogen and it makes up more than 60% of soy …
[HTML][HTML] Bitter taste signaling in cancer
Pharmacoresistance of cancer cells to many drugs used in chemotherapy remains a major
challenge for the treatment of cancer. Multidrug resistance transporters, especially ATP …
challenge for the treatment of cancer. Multidrug resistance transporters, especially ATP …