Given the complexity of human left heart anatomy and valvular structures, the fluid–structure
interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for …

The field of heart valve biomechanics is a rapidly expanding, highly clinically relevant area
of research. While most valvular pathologies are rooted in biomechanical changes, the …

Objectives The aim of this study was to evaluate flow dynamics in the aortic sinus and the
neosinus (NS) after transcatheter heart valve (THV) implantation in valve-in-valve (ViV) …

Purpose Leaflet thrombosis is a significant adverse event after transcatheter aortic valve
(TAV) replacement (TAVR). The purpose of our study was to present a semi-empirical …

Cardiovascular system diseases, as aortic valve stenosis, are the main cause of mortality
and morbidity among patients. There is still a room for enhancement of the diagnostic and …

Pressure recovery downstream of the aortic valve constitutes an important factor affecting
the calculation of pressure gradient (PG) across the valve and therefore the accuracy of the …

Background and objective Coronary artery diseases and aortic valve stenosis are two of the
main causes of mortality and morbidity worldwide. Stenosis of the aortic valve develops due …

Coexisting hypertension and aortic stenosis are common. Some studies showed that
elevated blood pressures may be associated with progression of calcific aortic valve disease …

Aging and calcific aortic valve disease (CAVD) are the main factors leading to aortic
stenosis. Both processes are accompanied by growth and remodeling pathways that play a …

The aortic valve is a highly dynamic structure characterized by a transvalvular flow that is
unsteady, pulsatile, and characterized by episodes of forward and reverse flow patterns …