Nonadherent splenic lymphoid cells from tumor-bearing animals exhibit a poor primary in
vitro plaque-forming cell (PFC) response to SRBC. This is attributable to the presence, in this …

Suppressor cell activity is induced by the addition of prostaglandin E 1 to normal mouse
spleen cells (NSC). When this population is added to fresh NSC, it suppresses the primary in …

Two prototype target determinants for unrestricted killing by T cells are defined: Qed‐la,
detected on B6. Tlaa targets by C3H/HeJ lymphocytes primed in vivo and restimulated in …

The cytotoxic response to TNP-modified syngeneic cells is small compared to the cytotoxic
response to alloantigens. Limiting dilution analyses indicate that the number of lymphocytes …

Suppressor cells, which specifically suppress the in vitro response of syngeneic spleen cells
to the DBA/2 mastocytoma, P815, were identified in the spleens of DBA/2 mice injected …

The recently discovered B6. C‐H‐2bm12 (bm12) histocompatibility mutant bears a mutation
of the I‐A subregion of the H‐2b haplotype. We have studied cytotoxic T lymphocytes (CTL) …

Depletion of adherent cells from stimulator and responder lymphocyte by a single filtration
through nylon wool columns, led to complete abrogation of the cytotoxic response to the …

We have investigated cell-mediated immune responses to cultured human T-and B-cell
lines. Two effector mechanisms were explored and found to have different capabilities for …

Cytotoxic T lymphocytes (CTLs) to EL4, a syngeneic lymphocytic leukemia of C57BL/6
(B6)(H-2 b) mice, were obtained by culturing normal B6 spleen cells with irradiated EL4 …

Abstract A cosmid (cos a 13.1) containing RT1 class II B alpha and B beta genes was
introduced into mouse and rat fibroblast cell lines by transformation. Mouse L cells …