[HTML][HTML] The two sides of chromosomal instability: drivers and brakes in cancer
R Hosea, S Hillary, S Naqvi, S Wu… - Signal Transduction and …, 2024 - nature.com
Chromosomal instability (CIN) is a hallmark of cancer and is associated with tumor cell
malignancy. CIN triggers a chain reaction in cells leading to chromosomal abnormalities …
malignancy. CIN triggers a chain reaction in cells leading to chromosomal abnormalities …
[HTML][HTML] Metformin in Esophageal Carcinoma: Exploring Molecular Mechanisms and Therapeutic Insights
SP Papadakos, A Argyrou, V Lekakis… - International Journal of …, 2024 - mdpi.com
Esophageal cancer (EC) remains a formidable malignancy with limited treatment options
and high mortality rates, necessitating the exploration of innovative therapeutic avenues …
and high mortality rates, necessitating the exploration of innovative therapeutic avenues …
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett's oesophagus surveillance: individual-level data analysis
EL Black, E Ococks, G Devonshire, AWT Ng… - Gut, 2024 - gut.bmj.com
Objective Whether gastric metaplasia (GM) of the oesophagus should be considered as
Barrett's oesophagus (BO) is controversial. Given concern intestinal metaplasia (IM) may be …
Barrett's oesophagus (BO) is controversial. Given concern intestinal metaplasia (IM) may be …
Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data
B Lu - Cancer Pathogenesis and Therapy, 2024 - mednexus.org
Cancer is an evolutionary process involving the accumulation of diverse somatic mutations
and clonal evolution over time. Phylogenetic inference from samples obtained from an …
and clonal evolution over time. Phylogenetic inference from samples obtained from an …
Cell-cycle dependent DNA repair and replication unifies patterns of chromosome instability
Chromosomal instability (CIN) is pervasive in human tumours and often leads to structural or
numerical chromosomal aberrations. Somatic structural variants (SVs) are intimately related …
numerical chromosomal aberrations. Somatic structural variants (SVs) are intimately related …