In metastatic colorectal cancer (mCRC), an improved understanding of the underlying
pathology and molecular biology has successfully merged with advances in diagnostic …

Traditional approaches to sequence analysis are widely used to guide therapy for patients
with lung and colorectal cancer and for patients with melanoma, sarcomas (eg …

Colorectal cancer (CRC) is a prevalent and potentially fatal disease categorized based on
its high incidences and mortality rates, which raised the need for effective diagnostic …

RAD51 is the central protein in the homologous recombination pathway and is therefore of
great relevance in terms of both therapy resistance as well as genomic stability. By using a …

Purpose: Neoadjuvant chemoradiotherapy (neoCRT) is a standard treatment for locally
advanced rectal cancer (LARC); however, resistance to chemoradiotherapy is one of the …

Colorectal cancer is one of the commonest types of cancer and there is requirement for the
identification of prognostic biomarkers. In this study protein expression profiles have been …

The use of nanotechnology for drug delivery in cancer therapy has raised high expectations.
Additionally, the use of nanomaterials in sensors to extract and detect tumor specific …

BACKGROUND: The activated leukocyte cell adhesion molecule (ALCAM, CD166) has
been reported to be involved in tumorigenesis of colorectal cancer (CRC) and to function as …

DNA sequence analysis has become a significant laboratory test in oncology, permitting
treatment to become increasingly personalized for both solid tumors and hematologic …

Colorectal cancer is a major health burden, and a leading cause of cancer-related deaths in
industrialized countries. The steady improvements in surgery and chemotherapy have …