Depression heterogeneity and its biological underpinnings: toward immunometabolic depression

Y Milaneschi, F Lamers, M Berk, BWJH Penninx - Biological psychiatry, 2020 - Elsevier
Epidemiological evidence indicates the presence of dysregulated homeostatic biological
pathways in depressed patients, such as increased inflammation and disrupted energy …

The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders

DN Jones, MA Raghanti - Journal of Chemical Neuroanatomy, 2021 - Elsevier
Monoamine oxidase enzymes are responsible for the degredation of serotonin, dopamine,
and norepinephrine in the central neurvous system. Although it has been nearly 100 years …

Mental health in UK Biobank–development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis

KAS Davis, JRI Coleman, M Adams, N Allen… - BJPsych …, 2020 - cambridge.org
BackgroundUK Biobank is a well-characterised cohort of over 500 000 participants including
genetics, environmental data and imaging. An online mental health questionnaire was …

[HTML][HTML] Overweight, obesity, and individual symptoms of depression: a multicohort study with replication in UK Biobank

P Frank, M Jokela, GD Batty, C Lassale… - Brain, behavior, and …, 2022 - Elsevier
Objectives Obesity is associated with increased risk of depression, but the extent to which
this association is symptom-specific is unknown. We examined the associations of …

Exploring the heart–mind connection: unraveling the shared pathways between depression and cardiovascular diseases

J Sobolewska-Nowak, K Wachowska, A Nowak… - Biomedicines, 2023 - mdpi.com
Civilization diseases are defined as non-communicable diseases that affect a large part of
the population. Examples of such diseases are depression and cardiovascular disease …

Depression subtypes and obesity in adults: a systematic review and meta‐analysis

DA Silva, ESF Coutinho, LO Ferriani… - Obesity …, 2020 - Wiley Online Library
Examining clinical features of depressive episodes may help elucidating the nature of
association between depression and obesity, related to specific symptoms such as appetite …

Identification of risk groups for mental disorders, headache and oral behaviors in adults during the COVID-19 pandemic

M Wieckiewicz, D Danel, M Pondel, J Smardz… - Scientific reports, 2021 - nature.com
The dramatically changing situation during COVID-19 pandemic, is anticipated to provoke
psycho-emotional disturbances and somatization arising from the current epidemiological …

Higher adiposity and mental health: causal inference using Mendelian randomization

F Casanova, J O'Loughlin, S Martin… - Human molecular …, 2021 - academic.oup.com
Higher adiposity is an established risk factor for psychiatric diseases including depression
and anxiety. The associations between adiposity and depression may be explained by the …

[HTML][HTML] Relationship between major depression symptom severity and sleep collected using a wristband wearable device: multicenter longitudinal observational …

Y Zhang, AA Folarin, S Sun, N Cummins… - JMIR mHealth and …, 2021 - mhealth.jmir.org
Background Sleep problems tend to vary according to the course of the disorder in
individuals with mental health problems. Research in mental health has associated sleep …

[HTML][HTML] Microbiome and immuno-metabolic dysregulation in patients with major depressive disorder with atypical clinical presentation

A Refisch, ZD Sen, TE Klassert, A Busch, B Besteher… - …, 2023 - Elsevier
Abstract Depression is highly prevalent (6% 1-year prevalence) and is the second leading
cause of disability worldwide. Available treatment options for depression are far from …