[HTML][HTML] Experimental murine models for colorectal cancer research

Í Neto, J Rocha, MM Gaspar, CP Reis - Cancers, 2023 - mdpi.com
Simple Summary In its early stages, colorectal cancer (CRC) is a localized tumor, but when it
metastasizes, it has dramatic consequences. Murine models in CRC research are important …

[HTML][HTML] Cytotoxic Activities and the Allantoinase Inhibitory Effect of the Leaf Extract of the Carnivorous Pitcher Plant Nepenthes miranda

ES Lin, CY Huang - Plants, 2022 - mdpi.com
Nepenthes are carnivorous pitcher plants that have several ethnobotanical uses, such as
curing stomachache and fever. Here, we prepared different extracts from the stem, leaf, and …

[HTML][HTML] Anticancer and Antioxidant Activities of the Root Extract of the Carnivorous Pitcher Plant Sarracenia purpurea

YH Huang, WY Chiang, PJ Chen, ES Lin, CY Huang - Plants, 2022 - mdpi.com
The carnivorous pitcher plant Sarracenia purpurea exhibits many ethnobotanical uses,
including the treatments of type 2 diabetes and tuberculosis-like symptoms. In this study, we …

[HTML][HTML] Autophagy-related mechanisms for treatment of multiple myeloma

G Kozalak, A Koşar - Cancer Drug Resistance, 2023 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is a type of hematological cancer that occurs when B cells become
malignant. Various drugs such as proteasome inhibitors, immunomodulators, and …

[HTML][HTML] The inhibition activities of the fruit extract of Plinia cauliflora against melanoma cells and the single-stranded DNA-binding protein (SSB) from Klebsiella …

ES Lin, CY Huang - Applied Sciences, 2023 - mdpi.com
Plinia cauliflora has been associated with numerous ethnobotanical applications. In this
study, we uncovered that the fruit extract of P. cauliflora, obtained using 50% ethanol …

[HTML][HTML] Cytotoxic, Antibacterial, and Antioxidant Activities of the Leaf Extract of Sinningia bullata

PJ Chen, ES Lin, HH Su, CY Huang - Plants, 2023 - mdpi.com
Sinningia bullata is a tuberous member of the flowering plant family Gesneriaceae. Prior to
this work, the antibacterial, antioxidant, and cytotoxic properties of S. bullata were …

Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs

N Moskovits, E Itzhaki, N Tarasenko, E Chausky… - JoVE (Journal of …, 2022 - jove.com
Despite remarkable advances in understanding tumor biology, the vast majority of oncology
drug candidates entering clinical trials fail, often due to a lack of clinical efficacy. This high …