Towards in vitro models for reducing or replacing the use of animals in drug testing
Towards in vitro models for reducing or replacing the use of animals in drug testing | Nature
Biomedical Engineering Skip to main content Thank you for visiting nature.com. You are using …
Biomedical Engineering Skip to main content Thank you for visiting nature.com. You are using …
Microphysiological systems as reliable drug discovery and evaluation tools: Evolution from innovation to maturity
Microphysiological systems (MPSs), also known as organ-on-chip or disease-on-chip, have
recently emerged to reconstitute the in vivo cellular microenvironment of various organs and …
recently emerged to reconstitute the in vivo cellular microenvironment of various organs and …
[HTML][HTML] Complex or not too complex? One size does not fit all in next generation microphysiological systems
In the attempt to overcome the increasingly recognized shortcomings of existing in vitro and
in vivo models, researchers have started to implement alternative models, including …
in vivo models, researchers have started to implement alternative models, including …
Report of the assay guidance workshop on 3-dimensional tissue models for antiviral drug development
R Jordan, SL Ford-Scheimer… - The Journal of …, 2023 - academic.oup.com
Abstract The National Center for Advancing Translational Sciences (NCATS) Assay
Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development …
Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development …
From lab to society: Fostering clinical translation of molecular systems engineering
RGL da Silva, A Blasimme - Bioengineering & Translational …, 2024 - Wiley Online Library
Over the last decade, bioengineering has seen a sustained growth in scientific publications,
patents, and clinical trials. As the field attempts to bridge the gap between discovery and …
patents, and clinical trials. As the field attempts to bridge the gap between discovery and …
Comprehensive approaches to preclinical evaluation of monoclonal antibodies and their next-generation derivatives
Biotherapeutics hold great promise for the treatment of severe diseases and offer innovative
possibilities for new treatments that target previously unaddressed medical needs. Despite …
possibilities for new treatments that target previously unaddressed medical needs. Despite …
[HTML][HTML] Potential value of animal microphysiological systems
PC Brown, BH Hooberman, BL Skinner… - ALTEX-Alternatives to …, 2024 - altex.org
Microphysiological systems (MPS) are designed to recapitulate aspects of tissue/organ
physiology in vivo, thereby providing potential value in safety and efficacy assessments of …
physiology in vivo, thereby providing potential value in safety and efficacy assessments of …
Pancreatic Islet Microphysiology System for Disease Modeling of Type 2 Diabetes
CR Wiegand - 2023 - search.proquest.com
Diabetes has become an increasingly prominent global issue afflicting 10% of world's
population where type 2 diabetes (T2D) comprises the majority of those diagnosed. T2D …
population where type 2 diabetes (T2D) comprises the majority of those diagnosed. T2D …
[HTML][HTML] Your Body, Your Treatment: The Clinical Potential of Microphysiological Systems in Personalized Medicine
L Taye - jhutoxicologypolicyresearch.org
Personalized medicine targets a patient's unique characteristics to provide more accurate
diagnoses and effective treatment. Prevention, diagnosis, and progression for a single …
diagnoses and effective treatment. Prevention, diagnosis, and progression for a single …