[HTML][HTML] Actin-associated proteins and small molecules targeting the actin cytoskeleton
J Gao, F Nakamura - International journal of molecular sciences, 2022 - mdpi.com
Actin-associated proteins (AAPs) act on monomeric globular actin (G-actin) and polymerized
filamentous actin (F-actin) to regulate their dynamics and architectures which ultimately …
filamentous actin (F-actin) to regulate their dynamics and architectures which ultimately …
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer
A Wang, Y Wang, X Meng, Y Yang - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
Prostate cancer (PC) is the most common malignancy in men worldwide. Here, two series of
novel thiohydantoin derivatives of enzalutamide as potent androgen receptor (AR) …
novel thiohydantoin derivatives of enzalutamide as potent androgen receptor (AR) …
Synthesis and evaluation of N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl analogous as anticancer, anti-angiogenic & antioxidant …
AS Sawant, SS Kamble, PM Pisal, SS Sawant… - … Biology and Chemistry, 2021 - Elsevier
Abstract N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl
analogues (flutamides) are versatile scaffolds with a wide spectrum of biological activities. A …
analogues (flutamides) are versatile scaffolds with a wide spectrum of biological activities. A …
Assessment of factors predicting disease progression in Japanese patients with non-metastatic castration-resistant prostate cancer
H Miyake, K Watanabe, Y Matsushita… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Despite recent introduction of several novel agents, limited data exist
regarding parameters that help predict the progression of non-metastatic castration-resistant …
regarding parameters that help predict the progression of non-metastatic castration-resistant …
[HTML][HTML] Determinación in vitro del efecto de algunas sustancias liquénicas seleccionadas sobre el receptor de andrógenos, la enzima 5alfa-reductasa y la aromatasa …
A Polania Patiño - 2020 - repositorio.unal.edu.co
Con la finalidad de contribuir al descubrimiento de fármacos para el tratamiento de
desórdenes dependientes de andrógenos endógenos como la hiperplasia prostática …
desórdenes dependientes de andrógenos endógenos como la hiperplasia prostática …
Asociación entre la expresión de akr1c3 y zeb1 y resistencia a terapia de depravación androgénica, en casos de adenocarcinoma prostático de un centro oncológico …
EY Manrique Julio - 2014 - repositorio.unicartagena.edu.co
El cáncer de próstata es una patología con alta mortalidad en el mundo, cuyo pronóstico
varía según la etapa; estudios sugieren que entre un 10 y un 20 por ciento de pacientes con …
varía según la etapa; estudios sugieren que entre un 10 y un 20 por ciento de pacientes con …